肾血管栓塞术与手术治疗高度肾创伤:全国范围内的对比分析。

IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE European Journal of Trauma and Emergency Surgery Pub Date : 2024-08-30 DOI:10.1007/s00068-024-02641-5
Matthew K Simpson, Emanuele Lagazzi, Vahe S Panossian, Ikemsinachi C Nzenwa, Helen S Wei, Wardah Rafaqat, Anne H Hoekman, Michael P DeWane, George C Velmahos, John O Hwabejire
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引用次数: 0

摘要

目的:肾血管栓塞术(RAE)广泛应用于低级别肾损伤,可改善患者预后,而手术仍是处理高级别损伤的主要方法。我们比较了高级别肾创伤(HGRT)手术和 RAE 治疗后的疗效:我们使用 ACS TQIP 2016-2020 来识别年龄≥16 岁、接受 RAE 或手术的 HGRT 患者。发病率是主要结果,死亡率和住院时间是次要结果。我们通过多层次逻辑回归分析考虑了临床相关特征:我们纳入了 591 名患者,其中 279 人(47.2%)接受了 RAE。经调整后,发病率、住院时间或重症监护室住院时间均无差异。与 RAE 相比,手术组的死亡率增加(aOR 4.93;[95% CI] 1.53-15.82;p = 0.007)。在穿透性损伤亚组中,没有观察到管理与结果之间的关联。在 V 级损伤亚组中,术后发病率明显更高(aOR 4.64;[95% CI] 1.49-14.47;p = 0.008):总体而言,RAE 对发病率的影响不大,但与死亡率的改善有关。RAE可以通过增强同期非手术干预的疗效来保护肾功能。需要进行随机研究来进一步验证 RAE 在 HGRT 中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Renal angioembolization vs. surgery for high-grade renal trauma: a nationwide comparative analysis.

Purpose: Renal angioembolization (RAE) is widely employed in low-grade renal injuries and associated with improved patient outcomes, while surgery remains the mainstay for managing high-grade injuries. We compared the outcomes following surgery and RAE in high-grade renal trauma (HGRT).

Methods: We used the ACS TQIP 2016-2020 to identify patients ≥ 16 years with HGRT who underwent RAE or surgery. Morbidity was the primary outcome, while mortality and lengths of stay were secondary outcomes. We accounted for clinically relevant characteristics using multilevel logistic regression analyses.

Results: We included 591 patients, of whom 279 (47.2%) underwent RAE. After adjusting, there was no difference in morbidity, hospital LOS, or ICU LOS. The surgery cohort had increased odds of mortality (aOR 4.93; [95% CI] 1.53-15.82; p = 0.007) compared to RAE. In the penetrating injury subgroup, no associations between management and outcomes were observed. In the grade V injury subgroup, morbidity was significantly higher after surgery (aOR 4.64; [95% CI] 1.49-14.47; p = 0.008).

Conclusion: Overall, RAE did not significantly impact morbidity but was associated with improved mortality. RAE could safeguard renal function by augmenting the efficacy of concurrent non-operative interventions. Randomized studies are needed to further validate the utility of RAE in HGRT.

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来源期刊
CiteScore
4.50
自引率
14.30%
发文量
311
审稿时长
3 months
期刊介绍: The European Journal of Trauma and Emergency Surgery aims to open an interdisciplinary forum that allows for the scientific exchange between basic and clinical science related to pathophysiology, diagnostics and treatment of traumatized patients. The journal covers all aspects of clinical management, operative treatment and related research of traumatic injuries. Clinical and experimental papers on issues relevant for the improvement of trauma care are published. Reviews, original articles, short communications and letters allow the appropriate presentation of major and minor topics.
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