评估 X 射线防护镜在核医学中处理放射性药物和护理病人时减少眼睛晶状体辐 射量的效果。

IF 1.9 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Global health & medicine Pub Date : 2024-08-31 DOI:10.35772/ghm.2024.01023
Tomoko Oikawa, Kaori Saito, Keiichi Kurihara, Daisuke Horikawa, Katsuhiko Uruno, Hironori Kajiwara, Shuhei Ohashi, Masatoshi Hotta, Naoyuki Yagi, Hideaki Kitamura, Shinichi Hasegawa, Ryogo Minamimoto
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引用次数: 0

摘要

本研究的目的是估算在处理放射性药物和与接受放射性药物的患者接触时眼球镜片受到的辐射剂量,并利用模型验证 X 射线防护镜在减轻此类辐射照射方面的作用。为了评估处理放射性药物时的辐照量,我们使用荧光玻璃剂量计在 30 厘米和 60 厘米的距离测量 99mTc、123I、131I、111In 和 18F 的相关辐射剂量,然后计算 3 毫米剂量当量率 (3DER)。然后,我们估算了各种情况下的剂量减少率,包括使用注射器防护罩和铅当量为 0.07、0.15、0.75 和 0.88 mmPb 的 X 射线防护镜,以及它们的组合应用。对于所有放射性核素和两种放射源距离,铅当量为 0.75 mmPb 的 X 射线防护镜都优于铅当量为 0.07 mmPb 和 0.15 mmPb 的防护镜。在 30 厘米距离内处理 131I 和 111In 时,0.88 mmPb 的 X 射线防护镜优于 0.75 mmPb 的防护镜。在其他情况下,0.88 mmPb 的 X 射线防护镜的屏蔽效果略有降低或没有明显的额外效果。X 射线防护镜对 131I 和 18F 的整体屏蔽效果并不明显,但同时使用注射器防护罩和 0.75 或 0.88 mmPb 的 X 射线防护镜可提高所有情况下的剂量降低率。在模拟病人护理时,0.88 mmPb 的 X 射线防护镜可减少约 50% 或更多的剂量。X 射线防护镜可以减少眼睛晶状体的 3DER,与注射器防护罩结合使用效果更好。在临床环境中处理所有五种核素时,使用 0.88 mmPb 铅当量来充分利用 X 射线防护镜的防护能力是有效的。
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Evaluation of X-ray protective goggles in mitigating eye lens radiation exposure during radiopharmaceutical handling and patient care in nuclear medicine.

The aim of this study is to estimate eye lens exposure dose when handling radiopharmaceuticals and interacting with patients receiving radiopharmaceuticals, and to verify the usefulness of X-ray protective goggles in mitigating such radiation exposure using phantoms. To evaluate radiation exposure during the handling of radiopharmaceuticals, we employed a fluorescent glass dosimeter to measure the radiation doses associated with 99mTc, 123I, 131I, 111In, and 18F at distances of 30 cm and 60 cm, followed by calculation of the 3 mm dose equivalent rate (3DER). We then estimated the dose reduction rates for various scenarios, including the use of syringe shields and X-ray protective goggles with lead equivalences of 0.07, 0.15, 0.75, and 0.88 mmPb, as well as their combined application. X-ray protective goggles with lead equivalence of 0.75 mmPb outperformed those with 0.07 mmPb and 0.15 mmPb, for all radionuclides and at both source distances. X-ray protective goggles with 0.88 mmPb outperformed those with 0.75 mmPb during handling of 131I and 111In at a distance of 30 cm. In the remaining scenarios, X-ray protective goggles with 0.88 mmPb resulted in marginal reductions or no discernible additional effects. The overall shielding effect of X-ray protective goggles was less pronounced for 131I and 18F, but the combined use of a syringe shield with X-ray protective goggles with 0.75 or 0.88 mmPb improved the dose reduction rate for all scenarios. In simulating patient care, X-ray protective goggles with 0.88 mmPb demonstrated a dose reduction effect of approximately 50% or more. X-ray protective goggles could reduce the 3DER for the eye lens, and were more effective when combined with a syringe shield. It is valid to use a lead equivalence of 0.88 mmPb to fully harness the protective capabilities of X-ray shielding goggles when dealing with all five types of nuclides in clinical settings.

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