窦状门静脉高压症的临床分析

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Iranian Journal of Medical Sciences Pub Date : 2024-08-01 DOI:10.30476/ijms.2023.99570.3164
Jie Zheng, Gang Luo, Ming Ming Deng
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引用次数: 0

摘要

背景:窦状门静脉高压症(SPH)是唯一一种完全可以治愈的门静脉高压症。然而,它很容易引起食管和/或胃的静脉曲张以及上消化道出血。本研究旨在探讨窦状门静脉高压症的临床特点和治疗方法:2019年9月至2021年9月期间,西南医科大学附属医院(中国泸州)对所有胰腺疾病患者进行了回顾性队列研究。研究收集并评估了所需信息,包括患者的人口统计学特征、血清实验室指标、影像学和内镜检查以及临床特征。结果以数字和百分比表示:在 830 名胰腺疾病患者中,61 人(7.3%)患上了 SPH。导致 SPH 的最常见原因是急性胰腺炎(80.3%),其次是慢性胰腺炎(11.5%)。脾静脉是最常受影响的静脉(45/61,73.8%)。造影剂增强计算机断层扫描(CECT)结果显示,51 例(83.6%)患者为胃底-胃体静脉曲张,3 例合并胃和食管静脉曲张。在胃周围侧支通道形成中,胃底静脉曲张(43/61,70.5%)最常见于 SPH 患者。脾肿大是 SPH 患者的常见表现(45.9%)。5例患者出现消化道静脉曲张出血:结论:SPH与脾静脉的通畅和独特的胃周侧静脉的形成有关。建议进行手术和/或内窥镜治疗,特别是对于出现大量消化道出血且保守治疗无效的患者。
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Clinical Analysis of Sinistral Portal Hypertension.

Background: Sinistral portal hypertension (SPH) is the only type of portal hypertension that is entirely curable. However, it can easily cause varicose veins in the esophagus and/or stomach, as well as upper gastrointestinal hemorrhage. This study aimed to investigate the clinical characteristics and treatments of sinistral portal hypertension.

Methods: All patients with pancreatic disease were included in this retrospective cohort study at the Affiliated Hospital of Southwest Medical University (Luzhou, China) from September 2019 to September 2021. The required information including the patient's demographics, serum laboratory indicators, imaging and endoscopy examinations, and clinical features were gathered and evaluated. The results were expressed as numbers and percentages.

Results: Out of the 830 patients with pancreatic diseases, 61 (7.3%) developed SPH. The most common cause of SPH was acute pancreatitis (80.3%), followed by chronic pancreatitis (11.5%). The splenic vein was the most frequently affected vein in patients (45/61, 73.8%). The findings of the contrast-enhanced computed tomography (CECT) indicated that 51 cases (83.6%) had gastric fundal-body varices, and three cases had combined gastric and esophageal varices. In the perigastric collateral channel formation, gastroepiploic varices (43/61, 70.5%) most frequently occurred in patients with SPH. Splenomegaly was a prevalent manifestation in SPH patients (45.9%). Five cases had gastrointestinal variceal hemorrhage.

Conclusion: SPH was associated with the patency of the splenic vein and the formation of distinctive perigastric collateral veins. Surgery and/or endoscopic treatment were recommended, particularly for patients who have experienced a significant amount of gastrointestinal bleeding and have failed conservative treatment.

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来源期刊
Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
0.00%
发文量
84
审稿时长
12 weeks
期刊介绍: The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of com­muni­cation for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science re­search experiences on prevalent diseases in the region and analysis of various regional problems.
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