{"title":"COVID 19 大流行对神经内科住院治疗的影响,分析继发于 COVID 19 和接种 COVID 19 疫苗的神经系统并发症。","authors":"Kosuke Matsuzono, Makiko Mieno, Takafumi Mashiko, Yuhei Anan, Tadashi Ozawa, Reiji Koide, Ryota Tanaka, Akio Kimura, Shigeru Fujimoto","doi":"10.1177/20503121241272518","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>We investigated the effect of the pandemic on neurological hospitalizations and complications associated with severe acute respiratory syndrome coronavirus 2 infection or vaccinations.</p><p><strong>Methods: </strong>We retrospectively analyzed data of patients hospitalized in our neurology division from 1 April 2019 to 31 March 2022 as the opt-out study. We classified the neurological diseases into nine subgroups, evaluated changes of neurological disease characteristics, and analyzed patients hospitalized with the complications from severe acute respiratory syndrome coronavirus 2 infection or after the coronavirus disease 2019 vaccination over three eras based on the pandemic stages: (1) pre-pandemic, (2) during the pandemic but before vaccines, and (3) during the pandemic with vaccines.</p><p><strong>Results: </strong>Overall, 1756 patients were included in the analyses. The patient characteristics significantly changed throughout the pandemic (<i>p</i> < 0.01). Although the number of autoimmune cases did not change throughout the pandemic (<i>p</i> = 0.53), that of psychological cases and that of unknown cases were significantly changed (<i>p</i> < 0.05, <i>p</i> < 0.01). There were four infectious cases and 11 cases following vaccination from 1 April 2020 to 31 March 2022. The 11 postvaccination cases involved 10 kinds of neurological diseases.</p><p><strong>Conclusions: </strong>The neurological characteristics significantly changed throughout the pandemic and there were diverse neurological complications following vaccinations.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363057/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of COVID 19 pandemic on the neurology department hospitalization with analysis of the neurological complications secondary to COVID 19 and vaccination against COVID 19.\",\"authors\":\"Kosuke Matsuzono, Makiko Mieno, Takafumi Mashiko, Yuhei Anan, Tadashi Ozawa, Reiji Koide, Ryota Tanaka, Akio Kimura, Shigeru Fujimoto\",\"doi\":\"10.1177/20503121241272518\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>We investigated the effect of the pandemic on neurological hospitalizations and complications associated with severe acute respiratory syndrome coronavirus 2 infection or vaccinations.</p><p><strong>Methods: </strong>We retrospectively analyzed data of patients hospitalized in our neurology division from 1 April 2019 to 31 March 2022 as the opt-out study. We classified the neurological diseases into nine subgroups, evaluated changes of neurological disease characteristics, and analyzed patients hospitalized with the complications from severe acute respiratory syndrome coronavirus 2 infection or after the coronavirus disease 2019 vaccination over three eras based on the pandemic stages: (1) pre-pandemic, (2) during the pandemic but before vaccines, and (3) during the pandemic with vaccines.</p><p><strong>Results: </strong>Overall, 1756 patients were included in the analyses. The patient characteristics significantly changed throughout the pandemic (<i>p</i> < 0.01). Although the number of autoimmune cases did not change throughout the pandemic (<i>p</i> = 0.53), that of psychological cases and that of unknown cases were significantly changed (<i>p</i> < 0.05, <i>p</i> < 0.01). There were four infectious cases and 11 cases following vaccination from 1 April 2020 to 31 March 2022. The 11 postvaccination cases involved 10 kinds of neurological diseases.</p><p><strong>Conclusions: </strong>The neurological characteristics significantly changed throughout the pandemic and there were diverse neurological complications following vaccinations.</p>\",\"PeriodicalId\":21398,\"journal\":{\"name\":\"SAGE Open Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363057/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SAGE Open Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/20503121241272518\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAGE Open Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/20503121241272518","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
目的我们调查了大流行对神经科住院患者的影响以及与严重急性呼吸系统综合征冠状病毒 2 感染或疫苗接种相关的并发症:我们回顾性分析了2019年4月1日至2022年3月31日在我院神经内科住院的患者数据,作为选择退出研究。我们将神经系统疾病分为九个亚组,评估了神经系统疾病特征的变化,并根据大流行阶段分析了三个时期因严重急性呼吸系统综合征冠状病毒 2 感染并发症或接种冠状病毒病 2019 年疫苗后住院的患者:(1) 大流行前;(2) 大流行期间但疫苗接种前;(3) 大流行期间接种疫苗后:共有 1756 名患者参与了分析。在整个大流行期间,患者的特征发生了明显变化(P P = 0.53),心理病例和未知病例的特征发生了明显变化(P P 结论):在整个大流行期间,神经系统特征发生了明显变化,接种疫苗后出现了多种神经系统并发症。
Effect of COVID 19 pandemic on the neurology department hospitalization with analysis of the neurological complications secondary to COVID 19 and vaccination against COVID 19.
Objective: We investigated the effect of the pandemic on neurological hospitalizations and complications associated with severe acute respiratory syndrome coronavirus 2 infection or vaccinations.
Methods: We retrospectively analyzed data of patients hospitalized in our neurology division from 1 April 2019 to 31 March 2022 as the opt-out study. We classified the neurological diseases into nine subgroups, evaluated changes of neurological disease characteristics, and analyzed patients hospitalized with the complications from severe acute respiratory syndrome coronavirus 2 infection or after the coronavirus disease 2019 vaccination over three eras based on the pandemic stages: (1) pre-pandemic, (2) during the pandemic but before vaccines, and (3) during the pandemic with vaccines.
Results: Overall, 1756 patients were included in the analyses. The patient characteristics significantly changed throughout the pandemic (p < 0.01). Although the number of autoimmune cases did not change throughout the pandemic (p = 0.53), that of psychological cases and that of unknown cases were significantly changed (p < 0.05, p < 0.01). There were four infectious cases and 11 cases following vaccination from 1 April 2020 to 31 March 2022. The 11 postvaccination cases involved 10 kinds of neurological diseases.
Conclusions: The neurological characteristics significantly changed throughout the pandemic and there were diverse neurological complications following vaccinations.