[基于有限元法的直接心室辅助加载模式研究]。

Chen Li, Xianjie Jiang, Sheng Zhang, Tianbo Wang, Xiaohan Liu, Yue Zhang, Gang Huang, Xiaogang Zhang, Junbo Xu, Zhongmin Jin
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引用次数: 0

摘要

为了研究直接心室辅助的生物力学效应并探索最佳加载模式,本研究基于有限元方法建立了心衰患者的左心室模型。研究提出了一种保持峰值压力压缩的加载模式,并从血液动力学和生物力学角度将其与传统的正弦加载模式进行了比较。结果表明,两种模式都能明显改善血液动力学参数,射血分数分别从基线的 29.33% 增加到 37.32% 和 37.77%,而峰值压力、每搏量和每搏功参数也有所提高。此外,两种模式在应力集中和纤维过度应变方面都有所改善。此外,考虑到辅助装置工作周期的相位误差,本研究中提出的辅助模式受到的影响较小。因此,这项研究可为直接心室辅助装置的设计和优化提供理论支持。
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[Study on direct ventricular assist loading mode based on a finite element method].

To investigate the biomechanical effects of direct ventricular assistance and explore the optimal loading mode, this study established a left ventricular model of heart failure patients based on the finite element method. It proposed a loading mode that maintains peak pressure compression, and compared it with the traditional sinusoidal loading mode from both hemodynamic and biomechanical perspectives. The results showed that both modes significantly improved hemodynamic parameters, with ejection fraction increased from a baseline of 29.33% to 37.32% and 37.77%, respectively, while peak pressure, stroke volume, and stroke work parameters also increased. Additionally, both modes showed improvements in stress concentration and excessive fiber strain. Moreover, considering the phase error of the assist device's working cycle, the proposed assist mode in this study was less affected. Therefore, this research may provide theoretical support for the design and optimization of direct ventricular assist devices.

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来源期刊
生物医学工程学杂志
生物医学工程学杂志 Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
4868
期刊介绍:
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