继发于静脉注射卡介苗(BCG)的播散性分枝杆菌病。

Harshdeep Harshad Acharya, Anupa Thampy, Rajiv Karthik, Priscilla Rupali
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引用次数: 0

摘要

卡介苗(Bacille Calmette-Guérin,BCG)已越来越多地用于免疫疗法,包括治疗非肌层浸润性膀胱癌,以及作为转移性前列腺癌和转移性黑色素瘤的辅助疗法。然而,因不慎静脉注射(而非膀胱内注射)而造成全身感染的情况并不常见,而且可能造成全身性后果。我们曾遇到过 3 名患者在静脉注射卡介苗后出现播散性牛分枝杆菌感染。
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Disseminated mycobacteriosis secondary to intravenous Bacille Calmette-Guérin (BCG) vaccine.

Bacille Calmette-Guérin (BCG) vaccine has been used increasingly in immunotherapy, including treatment of non-muscle-invasive bladder cancer, as an adjuvant therapy in metastatic prostate cancer and metastatic melanoma. However, systemic infection from inadvertent intravenous (instead of intravesical) injection is uncommon and can have systemic ramifications. We encountered 3 patients with disseminated Mycobacterium bovis infection that ensued after intravenous BCG injection.

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