血液透析患者中的一例罕见草履虫菌血症。

IF 2.4 4区 医学 Q2 UROLOGY & NEPHROLOGY Nephrology Pub Date : 2024-12-01 Epub Date: 2024-09-04 DOI:10.1111/nep.14385
Andrew M Fordyce, Frederiek Heenan-Vos, Tracey L Putt, Sine Donnellan, John W B Schollum, Robert J Walker
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引用次数: 0

摘要

Herbaspirillum spp.是一种常见的环境细菌,通常存在于土壤、植物根部和水中。它很少感染免疫力低下的患者,也很少报告感染免疫力正常的患者。我们报告了首例在非中性粒细胞减少的家庭血液透析患者中发生的赫伯斯比雷菌(Herbaspirillum huttiense)菌血症。一名 57 岁的男性患者在通过中心管路进行透析后,出现了 3 天的乏力、发热、全身僵硬和厌食症状,随后到我院就诊。经检查,他全身发热(体温 38.7°C)并伴有出血点,但没有其他感染迹象。血液培养显示存在多微生物感染,从中心管路中分离出液化沙雷氏菌和鸡冠状杆菌,从中心管路和外周血培养中分离出草吸虫。在移除中心静脉管后进行的外周血培养中分离出了胡提氏吸虫。对他家的供水和透析液进行的定期生物检测没有检测到非发酵革兰氏阴性杆菌的菌落形成单位。他最初接受了头孢曲松和万古霉素治疗,随后又接受了厄他培南和万古霉素治疗。拔除中心静脉置管 5 天后,他停止了静脉注射抗生素,并顺利康复。
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An unusual case of Herbaspirillum huttiense bacteraemia in a haemodialysis patient.

Herbaspirillum spp. is a common environmental bacterium usually found in soil, plant roots, and water. It is rarely associated with infection in immunocompromised patients, and rarely reported infections in immunocompetent patients. We report the first case of a Herbaspirillum huttiense bacteraemia in a non-neutropenic home haemodialysis patient. A 57-year-old male presented to our hospital with a 3-day history of malaise, fevers, rigours, and anorexia following dialysis through his central line. On examination, he was pyrexic (temperature 38.7°C) with splinter haemorrhages noted, but no other signs of infection were present. Blood cultures revealed a polymicrobial infection, with Serratia liquefaciens and Corynebacterium jeikeium isolated from the central line and Herbaspirillum sp. was isolated from both the central line and a peripheral culture. A later peripheral blood culture following central line removal isolated Herbaspirillum huttiense. Regular biological testing of his home water supply and dialysate detected no colony forming units of non-fermenting gram-negative bacilli. He was initially treated with ceftriaxone and vancomycin initially, followed by ertapenem and vancomycin. Intravenous antibiotics were ceased following 5 days after central line removal and he made an uneventful recovery.

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来源期刊
Nephrology
Nephrology 医学-泌尿学与肾脏学
CiteScore
4.50
自引率
4.00%
发文量
128
审稿时长
4-8 weeks
期刊介绍: Nephrology is published eight times per year by the Asian Pacific Society of Nephrology. It has a special emphasis on the needs of Clinical Nephrologists and those in developing countries. The journal publishes reviews and papers of international interest describing original research concerned with clinical and experimental aspects of nephrology.
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