胶质母细胞瘤的核医学成像技术。

IF 3.7 3区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Neurochemical Research Pub Date : 2024-09-05 DOI:10.1007/s11064-024-04233-6
Emirhan Harbi, Michael Aschner
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引用次数: 0

摘要

胶质母细胞瘤是中枢神经系统(CNS)最常见的原发性四级恶性肿瘤。此类肿瘤的治疗和管理需要采用多学科方法,而核医学技术在这一过程中发挥着重要作用。胶质母细胞瘤在目前的治疗方法下仍会复发,并对治疗产生耐药性,是存活率最低的肿瘤之一,存活期约为 8 个月。目前,胶质母细胞瘤的标准治疗方法是手术定位后的辅助化放疗。最近,核医学在胶质母细胞瘤领域取得了许多进展。正电子发射计算机断层扫描对于确定肿瘤定位、手术前计划、评估治疗后反应和检测复发至关重要。胶质母细胞瘤治疗的进步以及对该疾病生物学特性的深入了解促进了核医学技术的发展。除其他研究外,本综述旨在作为一般成像总结指南,并包括一些在胶质母细胞瘤中发现的新表达。本综述讨论了胶质母细胞瘤核医学的最新进展。
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Nuclear Medicine Imaging Techniques in Glioblastomas

Glioblastomas are the most common primary malignant grade 4 tumors of the central nervous system (CNS). The treatment and management of such tumors requires a multidisciplinary approach and nuclear medicine techniques play an important role in this process. Glioblastoma, which recurs despite current treatments and becomes resistant to treatments, is among the tumors with the lowest survival rate, with a survival rate of approximately 8 months. Currently, the standard treatment of glioblastoma is adjuvant chemoradiotherapy after surgical resection. There have been many recent advances in the field of Nuclear Medicine in glioblastoma. PET scans are critical in determining tumor localization, pre-surgical planning, evaluation of post-treatment response and detection of recurrence. Advances in the treatment of glioblastoma and a better understanding of the biological characteristics of the disease have contributed to the development of nuclear medicine techniques. This review, in addition to other studies, is intended as a general imaging summary guide and includes some new expressions discovered in glioblastoma. This review discusses recent advances in nuclear medicine in glioblastoma.

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来源期刊
Neurochemical Research
Neurochemical Research 医学-神经科学
CiteScore
7.70
自引率
2.30%
发文量
320
审稿时长
6 months
期刊介绍: Neurochemical Research is devoted to the rapid publication of studies that use neurochemical methodology in research on nervous system structure and function. The journal publishes original reports of experimental and clinical research results, perceptive reviews of significant problem areas in the neurosciences, brief comments of a methodological or interpretive nature, and research summaries conducted by leading scientists whose works are not readily available in English.
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