评估巴西圣保罗一家转诊中心孤立冠状动脉旁路移植手术的 EuroSCORE II 和 STS 评分表现以及手术紧迫性的影响。

Plínio José Whitaker Wolf, Vivian Lerner Amato
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引用次数: 0

摘要

导言:胸外科医师协会(STS)风险评分和欧洲心脏手术风险评估系统 II(EuroSCORE II)等风险预测模型被推荐用于评估冠状动脉旁路移植术(CABG)的手术死亡率。然而,它们在巴西的表现却令人怀疑:评估巴西参考中心的 STS 评分和 EuroSCORE II 在孤立的 CABG 中的表现:观察性和前瞻性研究:包括 438 名于 2022 年 5 月至 2023 年 5 月在但丁-帕赞内斯心脏病研究所接受孤立的 CABG 手术的患者。通过区分度(曲线下面积 [AUC])和校准度(观察/预期比值 [O/E])将观察死亡率与预测死亡率(STS评分和EuroSCORE II)进行比较,比较对象为总样本以及稳定型冠状动脉疾病(CAD)和急性冠状动脉综合征(ACS)亚组:观察死亡率为 4.3%(n=19),STS 和 EuroSCORE II 估计死亡率分别为 1.21% 和 2.74%。STS(AUC=0.646;95% 置信区间[CI] 0.760-0.532)和 EuroSCORE II(AUC=0.697;95% CI 0.802-0.593)的区分度较低。北美模式(PConclusion:在所有样本中,预测模型的表现并不理想,但EuroSCORE更胜一筹,尤其是在选择性稳定期患者中,其准确性令人满意。
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Assessment of EuroSCORE II and STS Score Performance and the Impact of Surgical Urgency in Isolated Coronary Artery Bypass Graft Surgery at a Referral Center in São Paulo, Brazil.

Introduction: Risk prediction models, such as The Society of Thoracic Surgeons (STS) risk score and the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II), are recommended for assessing operative mortality in coronary artery bypass grafting (CABG). However, their performance is questionable in Brazil.

Objective: To assess the performance of the STS score and EuroSCORE II in isolated CABG at a Brazilian reference center.

Methods: Observationaland prospective study including 438 patients undergoing isolated CABG from May 2022-May 2023 at the Instituto Dante Pazzanese de Cardiologia. Observed mortality was compared with predicted mortality (STS score and EuroSCORE II) by discrimination (area under the curve [AUC]) and calibration (observed/expected ratio [O/E]) in the total sample and subgroups of stable coronary artery disease (CAD) and acute coronary syndrome (ACS).

Results: Observed mortality was 4.3% (n=19) and estimated at 1.21% and 2.74% by STS and EuroSCORE II, respectively. STS (AUC=0.646; 95% confidence interva [CI] 0.760-0.532) and EuroSCORE II (AUC=0.697; 95% CI 0.802-0.593) presented poor discrimination. Calibration was absent for the North American mode (P<0.05) and reasonable for the European model (O/E=1.59, P=0.056). In the subgroups, EuroSCORE II had AUC of 0.616 (95% CI 0.752-0.480) and 0.826 (95% CI 0.991-0.661), while STS had AUC of 0.467 (95% CI 0.622-0.312) and 0.855 (95% CI 1.0-0.706) in ACS and CAD patients, respectively, demonstrating good score performance in stable patients.

Conclusion: The predictive models did not perform optimally in the total sample, but the EuroSCORE was superior, especially in elective stable patients, where accuracy was satisfactory.

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