皮肤酸性外壳:皮肤酸碱度的最新进展。

Sarah G Brooks, Rami H Mahmoud, Rachel R Lin, Joachim W Fluhr, Gil Yosipovitch
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引用次数: 0

摘要

酸幔概念是指位于皮肤上层角质层的缓冲系统。通过维持酸性环境,酸幔有助于调节微生物群、结构稳定性和炎症。皮肤的 pH 值是维持表皮屏障完整性的关键。pH 值的变化会破坏屏障的特性,最近的研究强调了它对皮肤病过程的影响。本综述探讨了皮肤 pH 值影响皮肤病病理机制的复杂关系。此外,我们还强调了 pH 值靶向疗法在促进皮肤病治疗方面的巨大潜力。
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The Skin Acid Mantle: An Update on Skin pH.

The acid mantle concept refers to the buffer system located in the upper stratum corneum of the skin. By sustaining an acidic environment, the acid mantle contributes to the regulation of the microbiome, structural stability, and inflammation. Skin pH is pivotal in maintaining the integrity of the epidermal barrier. Shifts in pH can disrupt barrier properties, and recent studies have emphasized its impact on dermatologic disease processes. This review explores the complex relationship of mechanisms through which skin pH impacts dermatologic pathologies. Furthermore, we highlight the promising potential of pH-targeted therapies for advancing the management of skin conditions.

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