继发性角膜瘢痕疙瘩:两例病例报告。

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Oxford Medical Case Reports Pub Date : 2024-09-07 eCollection Date: 2024-09-01 DOI:10.1093/omcr/omae105
Ali Sharifi, Touraj-Reza Mirshekari, Milad Azh, Hamid Sadeghi, Zahra Akbari, Amin Zand
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引用次数: 0

摘要

我们对两名患有角膜瘢痕疙瘩的男性患者进行了临床和组织学评估。其中一名患者曾因接触沸腾的葵花籽油而造成角膜外伤,另一名患者则接受过翼状胬肉切除术。裂隙灯检查发现,患者的角膜病变为单个、圆形、珍珠白结节,表面光滑。对切除的结节进行光镜分析,发现上皮细胞增生,鲍曼层破坏,基质中有排列不规则的大量胶原纤维。值得注意的是,在手术切除后的六个月内,两个病例的病变都没有复发。对于角膜结节隆起的患者,尤其是有眼表外伤或手术史的患者,应考虑将继发性角膜瘢痕疙瘩作为潜在的诊断依据。
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Secondary corneal keloid: a report of two cases.

We conducted clinical and histological evaluations on two male patients who presented with corneal keloid. One patient had a history of corneal trauma due to contact with boiling sunflower oil, while the other had undergone pterygium removal. Upon slit lamp examination, the corneal lesions were identified as single, well-circumscribed, pearly white nodules with a smooth surface. We successfully removed these nodules using a combination of superficial keratectomy and the application of mitomycin C. Light microscopy analysis of the excised nodules revealed hyperplastic epithelium, disrupted Bowman's layer, and irregularly arranged abundant collagen fibers within the stroma. Notably, there was no recurrence of the lesions in either case within six months following the surgical excision. Secondary corneal keloids should be considered as a potential diagnosis in patients with elevated corneal nodules, especially when there is a history of ocular surface trauma or surgery.

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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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