评估体重指数对食道旁疝修补术围手术期效果和短期复发的影响。

IF 2.6 3区 医学 Diseases of the Esophagus Pub Date : 2024-10-28 DOI:10.1093/dote/doae072
Shiwei Han, Taha Qaraqe, Charles Hillenbrand, Simo Du, Wesley Jenq, MadhanKumar Kuppusamy, Joel Sternbach, Michal Hubka, Donald E Low
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引用次数: 0

摘要

以往的评估表明,食道旁疝(PEH)修复手术的效果会受到肥胖程度增加的负面影响。更好地了解肥胖对食道旁疝修补术效果的影响,将有助于外科医生根据证据决定是否对患者进行手术。这项单一机构的回顾性队列研究纳入了 2000 年 1 月 1 日至 2020 年 6 月 30 日期间连续接受手术修复的 884 例巨大 PEH 患者。手术时记录了术前体重指数(BMI)。主要结果包括围手术期失血量、住院时间、主要并发症、早期疝复发和死亡率。手术时的平均年龄(标准差 [SD])为 68.4 (11.1),其中 645 例(73.0%)为女性。在 884 名患者中,有 875 名患者有术前即时体重指数(BMI)记录并纳入分析。平均(标清)体重指数为 29.24 (4.91) kg/m2。BMI 增加与围手术期失血量增加(系数,0.01;95% 置信区间 [CI],-0.01 至 0.02)、住院时间延长(系数,-0.01;95% 置信区间 [CI],-0.02 至 0.01)、复发疝发生率增加(几率比 [OR],1.03;95% 置信区间 [CI],0.95-1.10)或主要并发症增加(OR,0.93;95% 置信区间 [CI],0.82-1.05)均无关联。90 天死亡率为 0.3%。此外,与正常体重组相比,超重和各种程度的肥胖与不良预后无关。在接受PEH修复术的患者中,没有发现体重指数与围手术期结果或短期复发之间有任何关联。虽然术前减肥是明智之举,但较高的体重指数不应排除或延迟巨大 PEH 的手术治疗。
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Assessing the effect of body mass index on perioperative outcomes and short-term recurrence after paraesophageal hernia repair.

Previous assessments suggest that surgical results of paraesophageal hernia (PEH) repair were negatively impacted by increasing levels of obesity. A better understanding of the association of obesity on outcomes of PEH repair will support surgeons making evidence-based decisions on the surgical candidacy of individual patients. This single institution retrospective cohort study included 884 consecutive patients with giant PEH undergoing surgical repair between 1 January 2000 and 30 June 2020. Preoperative body mass index (BMI) was documented at the time of surgery. Main outcomes included perioperative blood loss, length of hospital stay, major complications, early hernia recurrence, and mortality. The mean (standard deviation [SD]) age at surgery was 68.4 (11.1), and 645 (73.0%) were women. Among the 884 patients, 875 had a documented immediate preoperative BMI and were included in the analysis. Mean (SD) BMI was 29.24 (4.91) kg/m2. Increasing BMI was not associated with increased perioperative blood loss (coefficient, 0.01; 95% confidence interval [CI], -0.01 to 0.02), prolonged length of stay (coefficient, -0.01; 95% CI, -0.02 to 0.01), increased incidence of recurrent hernia (odds ratio [OR], 1.03; 95% CI, 0.95-1.10), or increased major complications (OR, 0.93; 95% CI, 0.82-1.05). The 90-day mortality rate was 0.3%. Furthermore, when compared with the normal weight group, overweight and all levels of obesity were not related to unfavorable outcomes. No association was found between BMI and perioperative outcomes or short-term recurrence in patients undergoing PEH repair. Although preoperative weight loss is advisable, a higher BMI should not preclude or delay surgical management of giant PEH.

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来源期刊
Diseases of the Esophagus
Diseases of the Esophagus Medicine-Gastroenterology
自引率
7.70%
发文量
568
期刊介绍: Diseases of the Esophagus covers all aspects of the esophagus - etiology, investigation and diagnosis, and both medical and surgical treatment.
期刊最新文献
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