使用冻干羊膜贴片(LAMPatch)作为近视牵引性黄斑病变伴黄斑脱离患者主要手术的新技术。

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2024-09-02 eCollection Date: 2024-01-01 DOI:10.2147/OPTH.S469801
Abel Ramirez-Estudillo, Sergio Rojas-Juarez, Ximena Ramirez-Galicia, Angel Garcia-Vasquez, Silvia Medina-Medina, Rosario Gulias-Cañizo
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引用次数: 0

摘要

导言:病理性近视(PM)引起的黄斑病变正日益成为全球视力损伤和失明的原因。病理性近视与牵引性黄斑病变有关,其范围从黄斑窝沟炎到黄斑孔洞不等。这些疾病的治疗方法各不相同,治疗效果也不尽相同,因此需要新技术来解决近视性黄斑病变,并取得一致的治疗效果:方法:据报道,人羊膜(HAM)在眼内使用是安全的,而且能促进视网膜愈合,因此,在对患有与近视相关的不同牵引障碍的患者进行玻璃体旁切除术时,将其作为一种辅助手段。本研究对七名高度近视患者进行了前瞻性连续病例系列研究,这些患者接受了 25 号玻璃体切除术,并进行了 ILM 剥离和 HAM 移植:我们为期六个月的研究结果表明,这种新型技术在组织永久性方面取得了功能上的成功,且不会复发牵引,从而使视力的提高和维持优于其他技术。
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A Novel Technique Using Lyophilized Amniotic Membrane Patch (LAMPatch) as Primary Procedure in Patients with Myopic Traction Maculopathy with Macular Detachment.

Introduction: Maculopathy secondary to pathologic myopia (PM) is increasingly causing visual impairment and blindness worldwide. PM is associated with tractional maculopathy that ranges from macular foveoschisis to macular hole. These disorders are treated with different options that offer variable results, reflecting the need for new techniques that address myopic maculopathy with consistent outcomes.

Methods: Since human amniotic membrane (HAM) has been reported to be safe for intraocular use and to promote retinal healing, it was incorporated as an adjuvant in pars plana vitrectomy in patients with different tractional disorders related to myopia. This work presents a prospective, consecutive case series of seven patients with high myopia who underwent a 25-gauge vitrectomy with ILM peeling and HAM transplantation.

Results and discussion: Our six-month results show that this novel technique delivers functional success related to tissue permanence without recurrence of traction that translates into visual acuity gain and maintenance that are superior to other techniques.

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