原发性乳腺淋巴瘤:不常见部位常见肿瘤的病例报告。

IF 1.9 Q3 PATHOLOGY Clinical Pathology Pub Date : 2024-09-06 eCollection Date: 2024-01-01 DOI:10.1177/2632010X241276947
Alex Mremi, Hilary Chipongo, Ellyagape Urassa, Elifuraha Mkwizu, Jay Lodhia
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引用次数: 0

摘要

原发性乳腺淋巴瘤(PBL)是一种罕见的局限于乳腺的恶性淋巴肿瘤,约占所有乳腺恶性肿瘤的0.15%,占结外淋巴瘤的1.7%至2.2%。由于治疗方法不同,PBL 必须与传统的乳腺癌区分开来。一名 25 岁女性因左侧乳房肿块就诊。组织病理学和免疫组化检查确诊为弥漫大B细胞淋巴瘤(DLBCL)。她身体其他部位没有类似病变。她接受了一个周期的 R-CHOP 化疗,但在治疗过程中潜逃,之后在家中去世。通过采用利妥昔单抗等靶向药物、增加化疗方案、新药和个体化治疗技术,DLBCL 治疗的最新进展大大改善了患者的预后。PBL 的预后似乎更差;因此,在改善 PBL 患者的预后方面,延误治疗或放弃治疗令人严重关切。
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Primary Breast Lymphoma: A Case Report of a Common Tumor in an Uncommon Location.

Primary breast lymphoma (PBL) is a rare malignant lymphoid neoplasm limited to the breast, accounting for about 0.15% of all malignant breast tumors and 1.7% to 2.2% of extra-nodal lymphomas. PBL must be distinguished from conventional breast carcinomas due to different therapeutic approaches. A 25-year-old female presented with a left breast mass. Histopathology and immunohistochemical tests confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL). She had no similar lesions elsewhere in the body. She received 1 cycle of R-CHOP chemotherapy but absconded from the treatment and succumbed afterward while at home. Recent developments in DLBCL treatment have greatly improved patient outcomes by incorporating targeted medicines like rituximab, increased chemotherapy regimens, new drugs, and individualized treatment techniques. PBL appears to have a worse prognosis; thus, delay or abscondment from treatment is of serious concern when it comes to improving the prognosis of patients with PBL.

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来源期刊
Clinical Pathology
Clinical Pathology PATHOLOGY-
CiteScore
2.20
自引率
7.70%
发文量
66
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