八旬老人的单间室膝关节置换术:对 1 466 名患者进行的 2 年随访分析

IF 1.6 4区 医学 Q3 ORTHOPEDICS Knee Pub Date : 2024-09-10 DOI:10.1016/j.knee.2024.08.016
Alexander J. Acuña, Enrico M. Forlenza, Joseph Serino III, Vince K. Morgan, Tad L. Gerlinger, Craig J. Della Valle
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引用次数: 0

摘要

导言事实证明,在经过适当选择的患者中,膝关节非髁置换术(UKA)可改善疼痛和功能。有关八旬老人接受UKA后的疗效和并发症发生率的数据有限。方法在PearlDiver Mariner数据库中查询了2010-2022年间接受初级UKA的患者。根据性别、年份、Elixhauser 合并症指数 (ECI)、吸烟、肥胖和糖尿病,将 80 岁以上的患者与八旬老人队列(≥80 岁)进行 4:1 匹配。我们的分析共纳入了 1,334 名八旬老人和 5,313 名对照组。我们利用多变量逻辑回归对术后 90 天的内科并发症和术后 1 年和 2 年的外科并发症进行了比较。我们的回归分析对性别、ECI、吸烟、肥胖和糖尿病进行了控制。结果外科医生发生急性肾损伤(OR:2.306,95% CI:1.393-3.749;P <;0.001)、肺炎(OR:2.367,95% CI:1.301-4.189;p = 0.003)、UTI(OR:1.846,95% CI:1.304-2.583;p <;0.001)、术后 90 天的急诊就诊(OR:2.229,95% CI:1.586-3.105;p <;0.001)和任何并发症(OR:1.575,95% CI:1.304-1.895;p <;0.001)。八旬老人在 2 年后发生全因翻修的几率较低(OR:0.607,95% CI:0.382-0.923;P = 0.026)。2年后PJI(OR:0.832,95% CI:0.334-1.796;P = 0.664)、假体周围骨折(OR:0.516,95% CI:0.120-1.520;P = 0.289)或无菌性松动(OR:0.285,95% CI:0.045-1.203;P = 0.088)的发生率在不同队列之间没有差异。讨论这些研究结果表明,尽管术后急性期发生某些内科并发症的风险增加,但接受UKA手术的八旬老人在2年随访时的手术并发症发生率与年轻的匹配对照组相似。
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Unicompartmental knee arthroplasty in octogenarians: An analysis of 1,466 patients with 2-year follow-up

Introduction

Unicompartmental knee arthroplasty (UKA) has been shown to improve pain and function in appropriately selected patients. Limited data exists regarding outcomes and complication rates following UKA among octogenarians.

Methods

The PearlDiver Mariner database was queried for patients undergoing primary UKA between 2010–2022. Patients < 80 years old were matched 4:1 to the octogenarian cohort (≥80 years old) by sex, year, Elixhauser Comorbidity Index (ECI), tobacco use, obesity, and diabetes. A total of 1,334 octogenarians and 5,313 controls were included in our analysis. Multivariate logistic regression was utilized to compare medical complications at 90-days post-operatively and surgical complications at 1- and 2-years post-operatively. Our regression analysis controlled for sex, ECI, tobacco use, obesity, and diabetes.

Results

Octogenarians had an increased risk of acute kidney injury (OR: 2.306, 95% CI: 1.393–3.749; p < 0.001), pneumonia (OR: 2.367, 95% CI: 1.301–4.189; p = 0.003), UTI (OR: 1.846, 95% CI: 1.304–2.583; p < 0.001), ED visits (OR: 2.229, 95% CI: 1.586–3.105; p < 0.001), and any complication (OR: 1.575, 95% CI: 1.304–1.895; p < 0.001) at 90-days post-operatively. Octogenarians had lower odds of all-cause revision at 2-years (OR: 0.607, 95% CI: 0.382–0.923; p = 0.026). No differences were demonstrated between cohorts in rates of PJI (OR: 0.832, 95% CI: 0.334–1.796; p = 0.664), periprosthetic fracture (OR: 0.516, 95% CI: 0.120–1.520; p = 0.289), or aseptic loosening (OR: 0.285, 95% CI: 0.045–1.203; p = 0.088) at 2-years.

Discussion

These findings suggest that despite an increased risk of certain medical complications within the acute post-operative period, octogenarians undergoing UKA experienced similar rates of surgical complications to younger matched controls at 2-year follow-up.

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来源期刊
Knee
Knee 医学-外科
CiteScore
3.80
自引率
5.30%
发文量
171
审稿时长
6 months
期刊介绍: The Knee is an international journal publishing studies on the clinical treatment and fundamental biomechanical characteristics of this joint. The aim of the journal is to provide a vehicle relevant to surgeons, biomedical engineers, imaging specialists, materials scientists, rehabilitation personnel and all those with an interest in the knee. The topics covered include, but are not limited to: • Anatomy, physiology, morphology and biochemistry; • Biomechanical studies; • Advances in the development of prosthetic, orthotic and augmentation devices; • Imaging and diagnostic techniques; • Pathology; • Trauma; • Surgery; • Rehabilitation.
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