Objective Features Extracted from Motor Activity Time Series for Food Addiction Analysis Using Machine Learning

This study investigates machine learning algorithms to identify objective features for diagnosing food addiction (FA) and assessing confirmed symptoms (SC). Data were collected from 81 participants (mean age: 21.5 years, range: 18-61 years, women: 77.8%) whose FA and SC were measured using the Yale Food Addiction Scale (YFAS). Participants provided demographic and anthropometric data, completed the YFAS, the Zung Self-Rating Depression Scale, and the Dutch Eating Behavior Questionnaire, and wore an actimeter on the non-dominant wrist for a week to record motor activity. Analysis of the actimetric data identified significant statistical and entropy-based features that accurately predicted FA and SC using ML. The Matthews correlation coefficient (MCC) was the primary metric. Activity-related features were more effective for FA prediction (MCC=0.88) than rest-related features (MCC=0.68). For SC, activity segments yielded MCC=0.47, rest segments MCC=0.38, and their combination MCC=0.51. Significant correlations were also found between actimetric features related to FA, emotional, and restrained eating behaviors, supporting the model's validity. Our results support the concept of a human bionic suite composed of IoT devices and ML sensors, which implements health digital assistance with real-time monitoring and analysis of physiological indicators related to FA and SC.