经皮经肝胆囊引流术与经皮经肝胆道引流术治疗梗阻性黄疸的疗效比较

Tetsushi Azami, Yuichi Takano, Naoki Tamai, Jun Noda, Masataka Yamawaki, Fumitaka Niiya, Naotaka Maruoka, Fumiya Nishimoto, Akira Ishihara, Masatsugu Nagahama
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摘要

经皮经肝胆囊引流术(PTGBD)是经皮经肝胆管引流术(PTBD)的替代方法,适用于胆管阻塞在胆囊管汇合处以下的梗阻性黄疸病例。本研究旨在评估 PTGBD 和 PTBD 对梗阻性黄疸患者的作用。本研究招募了2017年1月至2024年3月期间在两家机构接受经皮胆道引流术治疗急性胆管炎和梗阻性黄疸的患者。55名患者被纳入本次分析。但是,排除了肝内或肝门胆管狭窄、胆总管结石术后、复杂性胆囊炎、总胆红素水平< 2.0 mg/dL、有无法纠正的出血倾向的患者,以及接受手术后未经穿刺而中止手术的患者。对手术的技术成功率、临床成功率和并发症发生率进行了评估。PTGBD 组的技术成功率为 96.3%(26/27),PTBD 组为 82.1%(13/28)。PTGBD组的临床成功率为85.2%(23/27),PTBD组为67.9%(19/28)。PTGBD 组的并发症发生率为 11.1%(3/27),PTBD 组为 17.9%(5/28)。因此,两组在任何终点上都没有明显差异。在阻塞性黄疸患者中,PTGBD 的疗效与 PTBD 相当。因此,对于阻塞性黄疸而又无法进行局部黄疸切开术的病例,局部黄疸分流术是一种合理的治疗方案。
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Outcomes of percutaneous transhepatic gallbladder drainage versus percutaneous transhepatic biliary drainage for obstructive jaundice
Percutaneous transhepatic gallbladder drainage (PTGBD) is an alternative to percutaneous transhepatic biliary drainage (PTBD) for cases of obstructive jaundice in which the bile duct obstruction is below the confluence of the cystic ducts. The present study aimed to evaluate the usefulness of PTGBD and PTBD in patients with obstructive jaundice. This study enrolled patients who had undergone percutaneous biliary drainage for acute cholangitis and obstructive jaundice at two institutions between January 2017 and March 2024. Fifty-five patients were included in this analysis. However, patients with intrahepatic or hilar bile duct stenosis, post choledocholithiasis, complex cholecystitis, total bilirubin levels < 2.0 mg/dL, and uncorrectable bleeding tendency and those who had undergone the procedure and later discontinued without puncture were excluded. The technical success rates, clinical success rates, and complication rates of the procedure were evaluated. The technical success rates were 96.3% (26/27) in the PTGBD group and 82.1% (13/28) in the PTBD group. The clinical success rates were 85.2% (23/27) in the PTGBD group and 67.9% (19/28) in the PTBD group. The complication rates were 11.1% (3/27) in the PTGBD group and 17.9% (5/28) in the PTBD group. Hence, the two groups did not significantly differ in any of the endpoints. The outcomes of PTGBD were comparable to those of PTBD in patients with obstructive jaundice. Hence, PTGBD is a reasonable treatment option for cases of obstructive jaundice in which PTBD is not feasible.
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