Maria T. Abreu, Maria A. Quintero, Luis Garces, Hajar Hazime, Rose Killian, Katerina M. Faust, Payton Mendygral, Judith Pignac-Kobinger, Cristiana Mangarelli, Ana M. Santander, Irina Fernández, Norma Solis, Mailenys Ortega, Oriana M. Damas, Siobhan Proksell, David H. Kerman, Amar R. Deshpande, Jennifer Seminerio, Jana A.L. Hashash, Philip Harvey, Ingrid Barrera, Tracy Crane
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引用次数: 0
摘要
背景克罗恩病(CD)以肠道炎症为特征。饮食是 CD 等炎症性肠病的一个危险因素,也是一种很有前景的辅助治疗方法,但目前针对 CD 患者的饮食干预研究很少。纤维可能有益处,但大多数 CD 患者被告知要避免食用高纤维食物。我们进行了一项纵向患者偏好研究,以考察低脂高纤维饮食(Mi-IBD 饮食)对 CD 症状、炎症和微生物组的影响。
A high-fiber, low-fat diet improves the symptoms and metabolic profile of patients with Crohn’s disease
Background Crohn’s disease (CD) is characterized by intestinal inflammation. Diet is a risk factor for inflammatory bowel diseases such as CD and represents a promising adjunctive treatment, yet there are few well-controlled dietary intervention studies in CD patients. Fiber may have beneficial effects; however, most CD patients are told to avoid high-fiber foods. We conducted a longitudinal patient-preference study to examine the effect of a catered low-fat, high- fiber diet (the Mi-IBD diet) on CD symptoms, inflammation, and the microbiome.