足球和职业培训是预防南非年轻男性感染艾滋病毒和滥用药物的无效策略:分组随机对照试验

IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH AIDS and Behavior Pub Date : 2024-09-11 DOI:10.1007/s10461-024-04458-0
Mary Jane Rotheram-Borus, Mark Tomlinson, Jackie Stewart, Zwelibanzi Skiti, Stephan Rabie, Jason Wang, Ellen Almirol, Lodewyk Vogel, Joan Christodoulou, Robert E. Weiss
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引用次数: 0

摘要

艾滋病毒和药物滥用在年轻男性中很常见,与一系列危险行为有关。然而,应对这些挑战的大多数服务都是在男性很少使用的环境中提供的,而且往往与男性身份不符。这项分组随机对照试验旨在减少南非开普敦郊区城镇地区年轻男性的多种危险行为。27 个社区中 18-29 岁的年轻男性(N = 1193)按地区随机接受与艾滋病相关的技能培训:(1)为期 12 个月的足球联赛(SL)干预;(2)6 个月的足球联赛,然后是 6 个月的职业培训(VT)干预(SL/VT,n = 9);或 3)对照条件(CC)。贝叶斯纵向混合模型用于评估随时间变化的行为。由于我们将多种结果作为主要结果,因此我们分析了在 18 个月的时间里(随访率分别为 83%、76% 和 61%),13 个测量条件之间显著不同结果的数量是否超过了偶然性。只有当 SL/VT 比 SL 有三个明显的优势时,其优势才是显著的。结果测量包括药物使用、艾滋病毒检测、保护性行为、暴力、社区参与和心理健康。在不同条件下,长期参与 SL 的比例通常在 45% 左右,但只有 17% 的男性完成了 SL/VT。根据研究结果的数量,在不同时期,不同条件之间没有明显差异。这些结构性干预措施在解决年轻男性药物滥用和艾滋病风险方面效果不佳:本试验于2014年11月24日在ClinicalTrials.gov(NCT02358226)进行了前瞻性注册。
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Soccer and Vocational Training are Ineffective Delivery Strategies to Prevent HIV and Substance Abuse by Young, South African Men: A Cluster Randomized Controlled Trial

HIV and substance abuse are common among young men, associated with a cluster of risk behaviors. Yet, most services addressing these challenges are delivered in setting underutilized by men and are often inconsistent with male identity. This cluster randomized controlled trial aimed to reduce multiple risk behaviors found among young men township areas on the outskirts of Cape Town, South Africa. Young men aged 18–29 years (N = 1193) across 27 neighborhoods were randomized by area to receive HIV-related skills training during either: (1) a 12-month soccer league (SL) intervention; (2) 6-month SL followed by 6 months of vocational training (VT) intervention (SL/VT, n = 9); or 3) a control condition (CC). Bayesian longitudinal mixture models were used to evaluate behaviors over time. Because we targeted multiple outcomes as our primary outcome, we analyzed if the number of significantly different outcomes between conditions exceeded chance for 13 measures over 18 months (with 83%, 76%, and 61% follow-up). Only if there were three significant benefits favoring the SL/VT over the SL would benefits be significant. Outcome measures included substance use, HIV-testing, protective sexual behaviors, violence, community engagement and mental health. Consistent participation in the SL was typically around 45% over time across conditions, however, only 17% of men completed SL/VT. There were no significant differences between conditions over time based on the number of study outcomes. These structural interventions were ineffective in addressing young men’s substance abuse and risk for HIV.

Clinical Trial Registration: This trial was prospectively registered on 24 November 2014 with ClinicalTrials.gov (NCT02358226).

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来源期刊
AIDS and Behavior
AIDS and Behavior Multiple-
CiteScore
6.60
自引率
13.60%
发文量
382
期刊介绍: AIDS and Behavior provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews. provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews.5 Year Impact Factor: 2.965 (2008) Section ''SOCIAL SCIENCES, BIOMEDICAL'': Rank 5 of 29 Section ''PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH'': Rank 9 of 76
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