部分保护的 N-糖基胺的合成和应用的最新进展

IF 1.7 3区 化学 Q3 CHEMISTRY, ORGANIC Current Organic Chemistry Pub Date : 2024-09-04 DOI:10.2174/0113852728316820240815164622
Sheersha Pradhan, Banoth Janhavi, Thangamuthu Mohan Das
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引用次数: 0

摘要

由于糖衍生物与各种支架的结合和进行化学修饰的兼容性,用于生物传感和生物标记、能量收集、药物设计和输送的创新工具的设计正在稳步发展。此外,在智能材料的应用方面,部分保护糖的化学性质还没有得到很好的探索。然而,这些糖衍生物在亲水性和疏水性之间具有独特的平衡特性,这使得它们可以作为凝胶分子发挥作用。有关合成和应用的几种合成策略已见诸文献。本综述主要关注部分受保护的单糖基 N-糖基胺及其应用,也有少量来自 O-糖苷和 C-糖苷的实例。
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Recent Advances in the Synthesis and Applications of Partially Protected N-Glycosylamines
Due to the compatibility of binding and undergoing chemical modification of sugar derivatives with a variety of scaffolds, the design of innovative tools for bio-sensing and bio-marking, energy harvesting, drug design, and delivery is growing steadily. Furthermore, the chemistry of partially protected sugars has not been explored well in terms of its applications in smart materials. However, these sugar derivatives possess a unique characteristic balance between hydrophilic and hydrophobic nature, which makes them act as gelator molecules. Several synthetic strategies pertaining to synthesis and applications are known in the literature. The present review mainly focuses on the partially protected monosaccharide-based N-glycosylamines and their applications, with few examples from O- and C-glycosides.
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来源期刊
Current Organic Chemistry
Current Organic Chemistry 化学-有机化学
CiteScore
3.70
自引率
7.70%
发文量
76
审稿时长
1 months
期刊介绍: Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.
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