奶山羊的乳脂调节:全面回顾

IF 2.4 4区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Biotechnology Pub Date : 2024-09-11 DOI:10.1007/s12033-024-01283-7
Bingzhi Li, Yu Li, Wanqiang Tian, Belete Kuraz Abebe, Sayed Haidar Abbas Raza, Hengwei Yu
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引用次数: 0

摘要

奶山羊是优质动物蛋白的重要来源,其生长发育和产奶性状受遗传和环境因素的综合影响很大。当务之急是确定支配具有经济价值性状的关键遗传位点,以加强育种计划。尽管基因组学技术不断进步,但有关遗传因素和环境影响之间相互作用的知识仍然存在空白,尤其是在牛奶产量和质量的调节方面。因此,本文旨在总结影响奶山羊产奶量和质量的遗传和环境因素方面的进展,并确定关键的调控机制。本综述总结了利用全基因组重测序鉴定与产奶性状相关的基因、利用转录组剖析鉴定与产奶相关的基因、探索山羊乳腺上皮细胞脂质代谢的调控机制以及评估营养因素对牛奶质量的影响等方面的最新进展。全面了解这些相互作用对于加强育种策略和确保奶山羊养殖业的可持续发展至关重要。未来的研究应结合多组学方法,揭示牛奶生产的复杂调控过程,并调整生产实践,以满足全球需求,同时维护经济和环境的可持续发展。
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Milk Lipid Regulation in Dairy Goats: A Comprehensive Review

The growth, development, and milk production traits of dairy goats, which are important sources of high-quality animal protein, are significantly influenced by a combination of genetic and environmental factors. It is imperative to identify key genetic loci that govern economically valuable traits in order to enhance breeding programs. Despite advancements in genomic technologies, there are still gaps in knowledge regarding the interplay between genetic factors and environmental influences, particularly in relation to the regulation of milk production and quality. Therefore, the aim of this paper was to synthesize advancements in the genetic and environmental factors affecting milk production and quality in dairy goats and identify key regulatory mechanisms. This review summarizes the recent progress on the identification of genes associated with milk production traits using whole-genome resequencing, the use of transcriptomic profiling to identify genes linked to milk production, the exploration of regulatory mechanisms of lipid metabolism in goat mammary epithelial cells, and the evaluation of the influence of nutritional factors on milk quality. A comprehensive understanding of these interactions is essential for enhancing breeding strategies and ensuring the sustainability of dairy goat farming. Future research should incorporate multi-omics approaches to unravel the intricate regulatory processes governing milk production and adapt practices to meet global demand while upholding economic and environmental sustainability.

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来源期刊
Molecular Biotechnology
Molecular Biotechnology 医学-生化与分子生物学
CiteScore
4.10
自引率
3.80%
发文量
165
审稿时长
6 months
期刊介绍: Molecular Biotechnology publishes original research papers on the application of molecular biology to both basic and applied research in the field of biotechnology. Particular areas of interest include the following: stability and expression of cloned gene products, cell transformation, gene cloning systems and the production of recombinant proteins, protein purification and analysis, transgenic species, developmental biology, mutation analysis, the applications of DNA fingerprinting, RNA interference, and PCR technology, microarray technology, proteomics, mass spectrometry, bioinformatics, plant molecular biology, microbial genetics, gene probes and the diagnosis of disease, pharmaceutical and health care products, therapeutic agents, vaccines, gene targeting, gene therapy, stem cell technology and tissue engineering, antisense technology, protein engineering and enzyme technology, monoclonal antibodies, glycobiology and glycomics, and agricultural biotechnology.
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