百草枯会导致慢性眼表毒性

IF 5.6 2区医学 Q1 OPHTHALMOLOGY Clinical and Experimental Ophthalmology Pub Date : 1993-08-01 DOI:10.1111/j.1442-9071.1993.tb00010.x

Kerry Vlahos BM, BS, Michael Goggin FRCSI, FCOphth, Douglas Coster FRACO, FRCS

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引用次数: 0

摘要

我们描述了一个局部接触百草枯商用溶液的病例。这可能是由于制剂中的表面活性剂促进了表面组织对除草剂的吸收，以及百草枯阳离子在细胞内的氧化还原循环。本文结合全身吸收的毒性对百草枯的眼部毒性进行了描述和解释。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Paraquat causes chronic ocular surface toxicity

We describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.

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来源期刊

Clinical and Experimental Ophthalmology 医学-眼科学

CiteScore

7.60

自引率

12.50%

发文量

150

审稿时长

4-8 weeks

期刊介绍： Clinical & Experimental Ophthalmology is the official journal of The Royal Australian and New Zealand College of Ophthalmologists. The journal publishes peer-reviewed original research and reviews dealing with all aspects of clinical practice and research which are international in scope and application. CEO recognises the importance of collaborative research and welcomes papers that have a direct influence on ophthalmic practice but are not unique to ophthalmology.