{"title":"减速能力和传统心率变异性在诊断血管迷走性晕厥中的有效性分析","authors":"Yongzhe Guo, Tao Lin, Nanyu Lin, Huizhong Lin","doi":"10.3389/fcvm.2024.1333684","DOIUrl":null,"url":null,"abstract":"BackgroundVasovagal syncope (VVS) is a prevalent medical condition with a lack of efficient methods for its detection.AimThis study aimed to explore an objective clinical indicator in diagnosing VVS.MethodsThe retrospective analysis involved clinical data of 243 syncope patients from 1 June 2020 to 31 July 2023. Among them, 108 patients had a negative result in the tilt test (TTT), while the remaining 135 patients had a positive result in the TTT. Relevant statistical methods were utilized to examine the correlation between VVS and different indicators of heart rate variability.ResultsAfter screening, 354 patients being considered for VVS were evaluated, resulting in a final sample size of 243. Sex, age, deceleration capacity (DC), and standard deviation of all normal-to-normal intervals (SDNNs) were the variables that showed statistical significance between the TTT(−) group and the TTT(+) group. Independent risk factors identified by multivariate logistic regression were DC [odds ratio (OR) 1.710, 95% confidence interval (CI) 1.388–2.106, <jats:italic>P</jats:italic> &lt; 0.001] and SDNN (OR 1.033, 95% CI 1.018–1.049, <jats:italic>P</jats:italic> &lt; 0.001). Comparing the groups, receiver operating characteristic analysis revealed a notable distinction in both DC and SDNN [the respective areas under the curve were 0.789 (95% CI 0.730–0.848) and 0.702 (95% CI 0.637–0.767); the cutoff values were 7.15 and 131.42; <jats:italic>P</jats:italic> &lt; 0.001, respectively].ConclusionIn summary, DC can function as an impartial and easily accessible clinical marker for differentiating VVS. A value exceeding 7.15 ms might suggest a higher likelihood of syncope.","PeriodicalId":12414,"journal":{"name":"Frontiers in Cardiovascular Medicine","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effectiveness analysis of deceleration capacity and traditional heart rate variability in diagnosing vasovagal syncope\",\"authors\":\"Yongzhe Guo, Tao Lin, Nanyu Lin, Huizhong Lin\",\"doi\":\"10.3389/fcvm.2024.1333684\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"BackgroundVasovagal syncope (VVS) is a prevalent medical condition with a lack of efficient methods for its detection.AimThis study aimed to explore an objective clinical indicator in diagnosing VVS.MethodsThe retrospective analysis involved clinical data of 243 syncope patients from 1 June 2020 to 31 July 2023. Among them, 108 patients had a negative result in the tilt test (TTT), while the remaining 135 patients had a positive result in the TTT. Relevant statistical methods were utilized to examine the correlation between VVS and different indicators of heart rate variability.ResultsAfter screening, 354 patients being considered for VVS were evaluated, resulting in a final sample size of 243. Sex, age, deceleration capacity (DC), and standard deviation of all normal-to-normal intervals (SDNNs) were the variables that showed statistical significance between the TTT(−) group and the TTT(+) group. Independent risk factors identified by multivariate logistic regression were DC [odds ratio (OR) 1.710, 95% confidence interval (CI) 1.388–2.106, <jats:italic>P</jats:italic> &lt; 0.001] and SDNN (OR 1.033, 95% CI 1.018–1.049, <jats:italic>P</jats:italic> &lt; 0.001). Comparing the groups, receiver operating characteristic analysis revealed a notable distinction in both DC and SDNN [the respective areas under the curve were 0.789 (95% CI 0.730–0.848) and 0.702 (95% CI 0.637–0.767); the cutoff values were 7.15 and 131.42; <jats:italic>P</jats:italic> &lt; 0.001, respectively].ConclusionIn summary, DC can function as an impartial and easily accessible clinical marker for differentiating VVS. A value exceeding 7.15 ms might suggest a higher likelihood of syncope.\",\"PeriodicalId\":12414,\"journal\":{\"name\":\"Frontiers in Cardiovascular Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Cardiovascular Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3389/fcvm.2024.1333684\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Cardiovascular Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fcvm.2024.1333684","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
背景血管迷走性晕厥(VVS)是一种普遍存在的内科疾病,目前缺乏有效的检测方法。其中,108 例患者倾斜试验(TTT)结果为阴性,其余 135 例患者倾斜试验结果为阳性。结果经过筛查,评估了 354 名考虑进行 VVS 的患者,最终样本量为 243 人。性别、年龄、减速能力(DC)和所有正常至正常间期的标准偏差(SDNNs)是在 TTT(-)组和 TTT(+)组之间显示出统计学意义的变量。多变量逻辑回归确定的独立风险因素是 DC [几率比(OR)1.710,95% 置信区间(CI)1.388-2.106,P < 0.001]和 SDNN(OR 1.033,95% CI 1.018-1.049,P < 0.001)。比较各组,接收器操作特征分析显示 DC 和 SDNN 均有显著差异[曲线下面积分别为 0.789 (95% CI 0.730-0.848) 和 0.702 (95% CI 0.637-0.767); 临界值分别为 7.15 和 131.42; P < 0.001]。超过 7.15 毫秒的数值可能表明晕厥的可能性较高。
Effectiveness analysis of deceleration capacity and traditional heart rate variability in diagnosing vasovagal syncope
BackgroundVasovagal syncope (VVS) is a prevalent medical condition with a lack of efficient methods for its detection.AimThis study aimed to explore an objective clinical indicator in diagnosing VVS.MethodsThe retrospective analysis involved clinical data of 243 syncope patients from 1 June 2020 to 31 July 2023. Among them, 108 patients had a negative result in the tilt test (TTT), while the remaining 135 patients had a positive result in the TTT. Relevant statistical methods were utilized to examine the correlation between VVS and different indicators of heart rate variability.ResultsAfter screening, 354 patients being considered for VVS were evaluated, resulting in a final sample size of 243. Sex, age, deceleration capacity (DC), and standard deviation of all normal-to-normal intervals (SDNNs) were the variables that showed statistical significance between the TTT(−) group and the TTT(+) group. Independent risk factors identified by multivariate logistic regression were DC [odds ratio (OR) 1.710, 95% confidence interval (CI) 1.388–2.106, P < 0.001] and SDNN (OR 1.033, 95% CI 1.018–1.049, P < 0.001). Comparing the groups, receiver operating characteristic analysis revealed a notable distinction in both DC and SDNN [the respective areas under the curve were 0.789 (95% CI 0.730–0.848) and 0.702 (95% CI 0.637–0.767); the cutoff values were 7.15 and 131.42; P < 0.001, respectively].ConclusionIn summary, DC can function as an impartial and easily accessible clinical marker for differentiating VVS. A value exceeding 7.15 ms might suggest a higher likelihood of syncope.
期刊介绍:
Frontiers? Which frontiers? Where exactly are the frontiers of cardiovascular medicine? And who should be defining these frontiers?
At Frontiers in Cardiovascular Medicine we believe it is worth being curious to foresee and explore beyond the current frontiers. In other words, we would like, through the articles published by our community journal Frontiers in Cardiovascular Medicine, to anticipate the future of cardiovascular medicine, and thus better prevent cardiovascular disorders and improve therapeutic options and outcomes of our patients.