Hiroki Oishi, Vladimir K. Berezovskii, Margaret S. Livingstone, Kevin S. Weiner, Michael J. Arcaro
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引用次数: 0
摘要
分布在灵长类颞下部皮层的一组相互连接的皮层区域形成了一个对人脸感知至关重要的网络。了解这一人脸网络的微观结构可以完善对单个区域如何发挥作用和相互作用以支持视觉感知的机理描述。为了解决这个问题,我们在猕猴身上获得了一个独特的数据集,该数据集结合了 fMRI 来定位体内的人脸斑块,然后通过体外组织学来解析同一个体不同皮层深度的组织架构。我们的研究结果表明,面斑块因细胞色素氧化酶(CO)而异,其次是髓鞘染色,中外侧(ML)面斑块表现出明显的 CO 染色。当使用概率定义面斑时,组织结构差异并不明显,这突出了在同一个体中整合体内和体外测量的精确绘图的重要性。这项研究表明,猕猴的面斑网络是由结构上不同的组成部分组成的。
Inferotemporal face patches are histo-architectonically distinct
An interconnected group of cortical regions distributed across the primate inferotemporal cortex forms a network critical for face perception. Understanding the microarchitecture of this face network can refine mechanistic accounts of how individual areas function and interact to support visual perception. To address this, we acquire a unique dataset in macaque monkeys combining fMRI to localize face patches in vivo and then ex vivo histology to resolve their histo-architecture across cortical depths in the same individuals. Our findings reveal that face patches differ based on cytochrome oxidase (CO) and, to a lesser extent, myelin staining, with the middle lateral (ML) face patch exhibiting pronounced CO staining. Histo-architectonic differences are less pronounced when using probabilistic definitions of face patches, underscoring the importance of precision mapping integrating in vivo and ex vivo measurements in the same individuals. This study indicates that the macaque face patch network is composed of architectonically distinct components.
期刊介绍:
Cell Reports publishes high-quality research across the life sciences and focuses on new biological insight as its primary criterion for publication. The journal offers three primary article types: Reports, which are shorter single-point articles, research articles, which are longer and provide deeper mechanistic insights, and resources, which highlight significant technical advances or major informational datasets that contribute to biological advances. Reviews covering recent literature in emerging and active fields are also accepted.
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The journal's professional in-house editors work closely with authors, reviewers, and the scientific advisory board, which consists of current and future leaders in their respective fields. The advisory board guides the scope, content, and quality of the journal, but editorial decisions are independently made by the in-house scientific editors of Cell Reports.