自组装 P38 肽抑制剂纳米粒子通过抑制铁蛋白沉积改善急性肾病向慢性肾病的转变 (Adv. Healthcare Mater. 23/2024)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL Advanced Healthcare Materials Pub Date : 2024-09-12 DOI:10.1002/adhm.202470149

Wang Xin, Shuiqin Gong, Yin Chen, Mengying Yao, Shaozong Qin, Jing Chen, Aihong Zhang, Wenrui Yu, Siyan Zhou, Bo Zhang, Jun Gu, Jinghong Zhao, Yinghui Huang

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自组装抑制肽纳米粒子

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Self-Assembling P38 Peptide Inhibitor Nanoparticles Ameliorate the Transition from Acute to Chronic Kidney Disease by Suppressing Ferroptosis (Adv. Healthcare Mater. 23/2024)

Self-Assembling Inhibitory Peptide Nanoparticles

In article 2400441, Jun Gu, Jinghong Zhao, Yinghui Huang, and co-workers devise a self-assembling p38 inhibitory peptide nanoparticle (TMNP), which exhibits renal targeting, ROS-scavenging, and ferroptosis-mitigating abilities, making it a promising therapeutic agent for the treatment of acute kidney injury (AKI) and its progression to chronic kidney disease (CKD).

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.