家族性高胆固醇血症孕妇不良妊娠结局的风险和使用他汀类药物的影响

medRxiv - Epidemiology Pub Date : 2024-09-04 DOI:10.1101/2024.09.03.24312275

Karianne Svendsen, Jacob Juel Christensen, Jannicke Igland, Henriette Walaas Krogh, Liv J. Mundal, David R. Jacobs, Martin P. Bogsrud, Kirsten B. Holven, Kjetil Retterstøl

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摘要

背景和目的关于家族性高胆固醇血症（FH）妇女可能存在不良妊娠结局风险的数据很少。我们研究了家族性高胆固醇血症诊断与不良妊娠结局之间的关系，以及他汀类药物在妊娠期的暴露与家族性高胆固醇血症女性不良妊娠结局之间的关系。

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Risk of adverse pregnancy outcomes and impact of statin use in pregnant women with familial hypercholesterolemia

Background and aims Sparse data exist on the possible risk of adverse pregnancy outcomes in women with familial hypercholesterolemia (FH). We investigated associations between having a FH diagnosis and adverse pregnancy outcomes, and between statin exposure in pregnancy and adverse pregnancy outcomes among women with FH.

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medRxiv - Epidemiology

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