经胸超声心动图在评估慢性阻塞性肺病右心室参数中的作用

Mohamed Ahmed Fouad Abdelalim, Mohamed A. Khalil, Ragia Samir Sharshr, Ayman Hassan Abdelzaher
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摘要

心脏症状是慢性阻塞性肺病(COPD)的特征之一,根据既定标准,慢性阻塞性肺病最近被认定为一种全身性疾病。这项研究的目的是调查经胸超声心动图在评估被诊断为慢性阻塞性肺病患者的右心室(RV)功能障碍方面的作用,并研究血液中 B 型钠尿肽(BNP)+ 的浓度与这一诊断程序之间的潜在相关性。研究人员对 80 名慢性阻塞性肺病患者和 20 名健康吸烟者进行了动脉血气、肺活量测定、超声心动图和血清 Pro BNP 检测,并将一些超声心动图参数与气流受限程度相关联。77.5%的慢性阻塞性肺病病例表现为肺动脉高压(PHTN),在对慢性阻塞性肺病患者进行分类时发现,II 组 65% 的患者有 PHTN,III 组 90% 的患者有 PHTN。肺动脉收缩压(SPAP)、平均肺动脉压(MPAP)、右心室中径(RVMD)、右心室基底径(RVBD)、右心室纵径(RVLD)、肺动脉瓣和主动脉瓣上方的右心室流出道(RVOT)、三尖瓣环平面收缩期偏移(TAPSE)以及 RVEF 在所有组别中均存在显著差异。1%的用力呼气容积(FEV)与(RVMD 和 RVBD)之间以及 Pro BNP 与(TAPSE 和 RVEF)之间均呈负相关。77.5%的慢性阻塞性肺病患者发现了 PHTN,它与 FEV1% 呈负相关。在病情稳定的慢性阻塞性肺病患者中,血清 Pro BNP 水平与 FEV1% 呈负相关。
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The role of transthoracic echocardiography in evaluating right ventricular parameters in chronic obstructive pulmonary disease
Cardiac symptoms are a characteristic feature of chronic obstructive pulmonary disease (COPD), a disorder with lately achieved recognition as a systemic illness according to established standards. The research’s objective was aimed at investigating the transthoracic echocardiography role in assessing right ventricular (RV) dysfunction among individuals diagnosed with COPD, as well as to examine the potential correlation between blood pro B-type natriuretic peptide (BNP) concentrations + and this diagnostic procedure. Arterial blood gasses, spirometry, echocardiography, and serum pro BNP were done for 80 COPD patients and 20 healthy smokers, and some echocardiographic parameters were correlated with degree of airflow limitation. 77.5% of COPD cases exhibited pulmonary hypertension (PHTN), and on classifying our COPD patients, it was found that 65% of patients in group II had PHTN and 90% of patients in group III had PHTN. Systolic pulmonary artery pressure (SPAP), mean pulmonary arterial pressure (MPAP), right ventricular mid diameter (RVMD), right ventricular basal diameter (RVBD), right ventricular longitudinal diameter (RVLD), right ventricular outflow tract (RVOT) above pulmonary and aortic valve, and tricuspid annular plane systolic excursion (TAPSE) along with RVEF exhibited a significant variance among all groups. A negative correlation was observed among forced expiratory volume (FEV) 1% and (RVMD as well as RVBD) and between Pro BNP and (TAPSE and RVEF). PHTN was found in 77.5% of COPD patients and is negatively correlated with FEV1%. Serum pro BNP level exhibits a negative correlation with FEV1% in stable COPD patients.
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