{"title":"伴有 Epstein-Barr 病毒脊髓炎的眼结核：病例报告","authors":"Fakhri Alahyari , Raheleh Halabian , Javad Hosseini Nejad","doi":"10.1016/j.imj.2024.100132","DOIUrl":null,"url":null,"abstract":"<div><p>Ocular tuberculosis (OTB) is a chronic eye infection caused by <em>Mycobacterium tuberculosis</em>. Some cases of myelitis are associated with <em>Epstein-Barr virus</em> (EBV), with 1-5% of EBV infections leading to neurologic complications. We describe a 34-year-old Iranian woman with OTB and EBV coinfection. Despite initial success with anti-TB agents, the disease progressed, necessitating enucleation. <em>Mycobacterium tuberculosis</em> was detected by a tuberculin coagulation test, and EBV was confirmed via polymerase chain reaction. MRI showed plaques in the spinal cord and brain. The patient was treated with anti-TB and antiretroviral agents. Recognizing TB in the differential diagnosis of EBV myelitis is crucial.</p></div>","PeriodicalId":100667,"journal":{"name":"Infectious Medicine","volume":"3 3","pages":"Article 100132"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772431X24000467/pdfft?md5=3bd8069dc0ad02ebfc30d16a4483f1e4&pid=1-s2.0-S2772431X24000467-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Ocular tuberculosis associated with Epstein-Barr virus myelitis: A case report\",\"authors\":\"Fakhri Alahyari , Raheleh Halabian , Javad Hosseini Nejad\",\"doi\":\"10.1016/j.imj.2024.100132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Ocular tuberculosis (OTB) is a chronic eye infection caused by <em>Mycobacterium tuberculosis</em>. Some cases of myelitis are associated with <em>Epstein-Barr virus</em> (EBV), with 1-5% of EBV infections leading to neurologic complications. We describe a 34-year-old Iranian woman with OTB and EBV coinfection. Despite initial success with anti-TB agents, the disease progressed, necessitating enucleation. <em>Mycobacterium tuberculosis</em> was detected by a tuberculin coagulation test, and EBV was confirmed via polymerase chain reaction. MRI showed plaques in the spinal cord and brain. The patient was treated with anti-TB and antiretroviral agents. Recognizing TB in the differential diagnosis of EBV myelitis is crucial.</p></div>\",\"PeriodicalId\":100667,\"journal\":{\"name\":\"Infectious Medicine\",\"volume\":\"3 3\",\"pages\":\"Article 100132\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772431X24000467/pdfft?md5=3bd8069dc0ad02ebfc30d16a4483f1e4&pid=1-s2.0-S2772431X24000467-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infectious Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772431X24000467\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772431X24000467","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ocular tuberculosis associated with Epstein-Barr virus myelitis: A case report
Ocular tuberculosis (OTB) is a chronic eye infection caused by Mycobacterium tuberculosis. Some cases of myelitis are associated with Epstein-Barr virus (EBV), with 1-5% of EBV infections leading to neurologic complications. We describe a 34-year-old Iranian woman with OTB and EBV coinfection. Despite initial success with anti-TB agents, the disease progressed, necessitating enucleation. Mycobacterium tuberculosis was detected by a tuberculin coagulation test, and EBV was confirmed via polymerase chain reaction. MRI showed plaques in the spinal cord and brain. The patient was treated with anti-TB and antiretroviral agents. Recognizing TB in the differential diagnosis of EBV myelitis is crucial.
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