{"title":"在埃塞俄比亚西南部抗逆转录病毒疗法诊所就诊的孕妇和哺乳期妇女对 B+ 方案护理的依从性差以及预防母婴传播的相关因素:基于设施的横断面研究","authors":"Nuredin Mohammed Guta , Miresa Guteta , Ashanafi Asefa , Sisay Tulu , Biruk Bogale , Gachana Midaksa , Abinet Abebe","doi":"10.1016/j.ijans.2024.100780","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Globally, over 90 % of newborns’ HIV infections occur through mother-to-child transmission. However, only 50 % of pregnant women living with HIV received effective antiretroviral regimens. So, this study aimed to assess poor adherence to option B+ care and associated factors for the prevention of mother-to-child transmission among pregnant and lactating mothers attending ART clinics in Southwestern Ethiopia.</p></div><div><h3>Methods and materials</h3><p>An institution-based cross-sectional study was conducted with a sample of 284 HIV+ pregnant and lactating mothers who were on the PMTCT follow-up in ART clinics in southwest Ethiopia. The data were entered using EPI Data Version 3.1 and exported to SPSS Version 25 for further analysis. Binary logistic regression models were employed to identify associated factors for poor adherence to option B+ care of PMTCT using AOR with the corresponding 95 % CI.</p></div><div><h3>Result</h3><p>The level of poor adherence to option B+ care in PMTCT was 12.6 %. The study showed that disclosure status [AOR: 0.16 [95 % CI; 0.05, 0.49]], forgetfulness [AOR = 10.5; 95 % CI [3.8, 29.5]], fear of drug side effects [AOR: 3.97 [95 % CI: [1.1, 10.4]], and fear of stigma and discrimination [AOR: 6.7, 95 % CI: [2.5, 17.7]] were significantly associated with adherence to option B+ care.</p></div><div><h3>Conclusions</h3><p>The prevalence of poor adherence to option B+ care in this study was high. Fear of drug side effects, fear of stigma and discrimination, forgetfulness, and disclosure status were factors significantly associated with adherence to option B+ care. Proper counseling and awareness creation on drug adherence were strongly recommended.</p></div>","PeriodicalId":38091,"journal":{"name":"International Journal of Africa Nursing Sciences","volume":"21 ","pages":"Article 100780"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214139124001264/pdfft?md5=71b600d0f14713b039731394e9c85181&pid=1-s2.0-S2214139124001264-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Poor adherence to the option B+ care and associated factors for the prevention of mother-to-child transmission among pregnant and lactating mothers attending ART clinics of Southwestern Ethiopia: A facility based cross-sectional study\",\"authors\":\"Nuredin Mohammed Guta , Miresa Guteta , Ashanafi Asefa , Sisay Tulu , Biruk Bogale , Gachana Midaksa , Abinet Abebe\",\"doi\":\"10.1016/j.ijans.2024.100780\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Globally, over 90 % of newborns’ HIV infections occur through mother-to-child transmission. However, only 50 % of pregnant women living with HIV received effective antiretroviral regimens. So, this study aimed to assess poor adherence to option B+ care and associated factors for the prevention of mother-to-child transmission among pregnant and lactating mothers attending ART clinics in Southwestern Ethiopia.</p></div><div><h3>Methods and materials</h3><p>An institution-based cross-sectional study was conducted with a sample of 284 HIV+ pregnant and lactating mothers who were on the PMTCT follow-up in ART clinics in southwest Ethiopia. The data were entered using EPI Data Version 3.1 and exported to SPSS Version 25 for further analysis. Binary logistic regression models were employed to identify associated factors for poor adherence to option B+ care of PMTCT using AOR with the corresponding 95 % CI.</p></div><div><h3>Result</h3><p>The level of poor adherence to option B+ care in PMTCT was 12.6 %. The study showed that disclosure status [AOR: 0.16 [95 % CI; 0.05, 0.49]], forgetfulness [AOR = 10.5; 95 % CI [3.8, 29.5]], fear of drug side effects [AOR: 3.97 [95 % CI: [1.1, 10.4]], and fear of stigma and discrimination [AOR: 6.7, 95 % CI: [2.5, 17.7]] were significantly associated with adherence to option B+ care.</p></div><div><h3>Conclusions</h3><p>The prevalence of poor adherence to option B+ care in this study was high. Fear of drug side effects, fear of stigma and discrimination, forgetfulness, and disclosure status were factors significantly associated with adherence to option B+ care. 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引用次数: 0
摘要
导言在全球范围内,90% 以上的新生儿艾滋病毒感染是通过母婴传播发生的。然而,只有 50% 的感染艾滋病毒的孕妇接受了有效的抗逆转录病毒疗法。因此,本研究旨在评估在埃塞俄比亚西南部抗逆转录病毒疗法诊所就诊的孕妇和哺乳期妇女在选择 B+ 护理方案时的不良依从性以及预防母婴传播的相关因素。方法和材料在埃塞俄比亚西南部的抗逆转录病毒疗法诊所,对 284 名接受预防母婴传播随访的艾滋病毒感染者孕妇和哺乳期妇女进行了基于机构的横断面研究。数据使用 EPI Data Version 3.1 输入,并导出到 SPSS Version 25 进行进一步分析。采用二元逻辑回归模型,以AOR和相应的95 % CI来确定坚持预防母婴传播B+护理方案不良的相关因素。4]、对耻辱和歧视的恐惧[AOR:6.7,95 % CI:[2.5,17.7]]与选择 B+ 护理的依从性显著相关。对药物副作用的恐惧、对耻辱和歧视的恐惧、遗忘和信息披露状况是与坚持选择 B+ 护理明显相关的因素。我们强烈建议就坚持服药问题提供适当的咨询并提高人们的认识。
Poor adherence to the option B+ care and associated factors for the prevention of mother-to-child transmission among pregnant and lactating mothers attending ART clinics of Southwestern Ethiopia: A facility based cross-sectional study
Introduction
Globally, over 90 % of newborns’ HIV infections occur through mother-to-child transmission. However, only 50 % of pregnant women living with HIV received effective antiretroviral regimens. So, this study aimed to assess poor adherence to option B+ care and associated factors for the prevention of mother-to-child transmission among pregnant and lactating mothers attending ART clinics in Southwestern Ethiopia.
Methods and materials
An institution-based cross-sectional study was conducted with a sample of 284 HIV+ pregnant and lactating mothers who were on the PMTCT follow-up in ART clinics in southwest Ethiopia. The data were entered using EPI Data Version 3.1 and exported to SPSS Version 25 for further analysis. Binary logistic regression models were employed to identify associated factors for poor adherence to option B+ care of PMTCT using AOR with the corresponding 95 % CI.
Result
The level of poor adherence to option B+ care in PMTCT was 12.6 %. The study showed that disclosure status [AOR: 0.16 [95 % CI; 0.05, 0.49]], forgetfulness [AOR = 10.5; 95 % CI [3.8, 29.5]], fear of drug side effects [AOR: 3.97 [95 % CI: [1.1, 10.4]], and fear of stigma and discrimination [AOR: 6.7, 95 % CI: [2.5, 17.7]] were significantly associated with adherence to option B+ care.
Conclusions
The prevalence of poor adherence to option B+ care in this study was high. Fear of drug side effects, fear of stigma and discrimination, forgetfulness, and disclosure status were factors significantly associated with adherence to option B+ care. Proper counseling and awareness creation on drug adherence were strongly recommended.
期刊介绍:
International Journal of Africa Nursing Sciences (IJANS) is an international scientific journal published by Elsevier. The broad-based journal was founded on two key tenets, i.e. to publish the most exciting research with respect to the subjects of Nursing and Midwifery in Africa, and secondly, to advance the international understanding and development of nursing and midwifery in Africa, both as a profession and as an academic discipline. The fully refereed journal provides a forum for all aspects of nursing and midwifery sciences, especially new trends and advances. The journal call for original research papers, systematic and scholarly review articles, and critical papers which will stimulate debate on research, policy, theory or philosophy of nursing as related to nursing and midwifery in Africa, technical reports, and short communications, and which will meet the journal''s high academic and ethical standards. Manuscripts of nursing practice, education, management, and research are encouraged. The journal values critical scholarly debate on issues that have strategic significance for educators, practitioners, leaders and policy-makers of nursing and midwifery in Africa. The journal publishes the highest quality scholarly contributions reflecting the diversity of nursing, and is also inviting international scholars who are engaged with nursing and midwifery in Africa to contribute to the journal. We will only publish work that demonstrates the use of rigorous methodology as well as by publishing papers that highlight the theoretical underpinnings of nursing and midwifery as it relates to the Africa context.