健康文本简化:用于消化系统癌症教育的注释语料库和新的强化学习策略

IF 4 2区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Journal of Biomedical Informatics Pub Date : 2024-09-16 DOI:10.1016/j.jbi.2024.104727
Md Mushfiqur Rahman , Mohammad Sabik Irbaz , Kai North, Michelle S. Williams, Marcos Zampieri, Kevin Lybarger
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引用次数: 0

摘要

目的:健康教育材料的阅读水平极大地影响了信息的可理解性和可获取性,尤其是对少数群体而言。许多患者教育资源的阅读水平和复杂程度超过了广泛接受的标准。因此,我们亟需高效的健康信息文本简化模式,以提高信息的传播和普及程度。方法:我们介绍了简化消化系统癌症(SimpleDC),这是一个为健康文本简化研究定制的癌症教育材料平行语料库,由美国癌症协会、美国疾病控制和预防中心以及美国国家癌症研究所的教育内容组成。该语料库包括 31 个网页和相应的人工简化版本。它包括 1183 个注释句对(361 个训练句对、294 个开发句对和 528 个测试句对)。利用 SimpleDC 和现有的 Med-EASi 语料库,我们探索了基于大型语言模型 (LLM) 的简化方法,包括微调、强化学习 (RL)、带人类反馈的强化学习 (RLHF)、领域适应和基于提示的方法。我们的实验包括 Llama 2、Llama 3 和 GPT-4。我们引入了一种新颖的 RLHF 奖励函数,该函数具有轻量级模型,当在无标签数据上进行训练时,该模型善于区分原始文本和简化文本。我们的 RLHF 奖励函数优于现有的 RL 文本简化奖励函数。这些结果表明,RL/RLHF 可以实现与微调相当的性能,并提高微调模型的性能。此外,这些方法还能有效地将域外文本简化模型调整到目标领域。结论:新开发的 SimpleDC 语料库将成为研究界的宝贵财富,尤其是在患者教育简化方面。本文介绍的 RL/RLHF 方法可以在无标签文本上有效地训练简化模型,并利用域外简化语料库。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Health text simplification: An annotated corpus for digestive cancer education and novel strategies for reinforcement learning

Objective:

The reading level of health educational materials significantly influences the understandability and accessibility of the information, particularly for minoritized populations. Many patient educational resources surpass widely accepted standards for reading level and complexity. There is a critical need for high-performing text simplification models for health information to enhance dissemination and literacy. This need is particularly acute in cancer education, where effective prevention and screening education can substantially reduce morbidity and mortality.

Methods:

We introduce Simplified Digestive Cancer (SimpleDC), a parallel corpus of cancer education materials tailored for health text simplification research, comprising educational content from the American Cancer Society, Centers for Disease Control and Prevention, and National Cancer Institute. The corpus includes 31 web pages with the corresponding manually simplified versions. It consists of 1183 annotated sentence pairs (361 train, 294 development, and 528 test). Utilizing SimpleDC and the existing Med-EASi corpus, we explore Large Language Model (LLM)-based simplification methods, including fine-tuning, reinforcement learning (RL), reinforcement learning with human feedback (RLHF), domain adaptation, and prompt-based approaches. Our experimentation encompasses Llama 2, Llama 3, and GPT-4. We introduce a novel RLHF reward function featuring a lightweight model adept at distinguishing between original and simplified texts when enables training on unlabeled data.

Results:

Fine-tuned Llama models demonstrated high performance across various metrics. Our RLHF reward function outperformed existing RL text simplification reward functions. The results underscore that RL/RLHF can achieve performance comparable to fine-tuning and improve the performance of fine-tuned models. Additionally, these methods effectively adapt out-of-domain text simplification models to a target domain. The best-performing RL-enhanced Llama models outperformed GPT-4 in both automatic metrics and manual evaluation by subject matter experts.

Conclusion:

The newly developed SimpleDC corpus will serve as a valuable asset to the research community, particularly in patient education simplification. The RL/RLHF methodologies presented herein enable effective training of simplification models on unlabeled text and the utilization of out-of-domain simplification corpora.

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来源期刊
Journal of Biomedical Informatics
Journal of Biomedical Informatics 医学-计算机:跨学科应用
CiteScore
8.90
自引率
6.70%
发文量
243
审稿时长
32 days
期刊介绍: The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.
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