罗得岛吸毒者偏好芬太尼的相关因素

IF 4 2区 社会学 Q1 SUBSTANCE ABUSE Harm Reduction Journal Pub Date : 2024-09-14 DOI:10.1186/s12954-024-01089-5
Siena C. Napoleon, Carolyn J. Park, Jacqueline Goldman, Yu Li, Jane A. Buxton, Alexandria Macmadu, Katie B. Biello, Julia Noguchi, Brandon D.L. Marshall
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引用次数: 0

摘要

芬太尼在不受管制的毒品供应中越来越普遍,是导致美国吸毒过量死亡的原因之一。本研究旨在描述和识别罗得岛州(RI)吸毒者(PWUD)对芬太尼偏好的相关性。通过双变量分析,我们考察了 2020 年 8 月至 2023 年 2 月期间参加罗德岛州处方药和非法药物研究的参与者在基线时芬太尼偏好与社会人口和社会心理特征之间的关联。芬太尼偏好根据对五点李克特量表的回答进行操作:"我更喜欢使用芬太尼或含有芬太尼的药物"。对这句话回答 "非常不同意"、"不同意 "或 "中立 "的参与者被归类为不喜欢使用芬太尼,而回答 "同意 "或 "非常同意 "的参与者被归类为喜欢使用芬太尼。在 506 名符合分析条件的吸毒者中,15% 的人表示首选芬太尼或含有芬太尼的药物。在双变量分析中,对芬太尼的偏好与以下因素呈正相关:年龄较小、白种人、终生有过用药过量史、有过注射吸毒史、上个月参加过药物使用治疗项目、上个月接受过阿片类药物使用障碍的药物治疗,以及对海洛因和冰毒的偏好(均 p < 0.05)。描述性数据进一步揭示了偏好芬太尼的原因,其中最主要的原因与药物的感知效果和避免戒断症状的愿望有关。只有相对较少的一部分研究参与者偏好含有芬太尼的药物。鉴于芬太尼污染在不受管制的毒品市场上的各种物质中越来越普遍,对吸毒和残废者来说,结果是他们在选择毒品方面的选择权越来越小;例如,人们可能由于供应受限和需要减轻戒断症状而被迫使用芬太尼,或者可能无意中使用了芬太尼。为减轻与芬太尼有关的危害,需要对残疾人采取新颖、更有效的干预措施,包括增加获得适合其年龄的减低危害计划(如芬太尼试纸和过量预防中心)的机会。
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Correlates of fentanyl preference among people who use drugs in Rhode Island
Fentanyl is increasingly pervasive in the unregulated drug supply and is a driver of drug overdose deaths in the United States. The aims of this study were to characterize and identify correlates of fentanyl preference among people who use drugs (PWUD) in Rhode Island (RI). Using bivariate analysis, we examined associations between fentanyl preference and sociodemographic and psychosocial characteristics at baseline among participants enrolled in the RI Prescription Drug and Illicit Drug Study from August 2020-February 2023. Fentanyl preference was operationalized based on responses to a five-point Likert scale: “I prefer using fentanyl or drugs that have fentanyl in them.” Participants who responded that they “strongly disagree,” “disagree,” or were “neutral” with respect to this statement were classified as not preferring fentanyl, whereas participants who responded that they “agree” or “strongly agree” were classified as preferring fentanyl. Among 506 PWUD eligible for inclusion in this analysis, 15% expressed a preference for fentanyl or drugs containing fentanyl as their drug of choice. In bivariate analyses, preference for fentanyl was positively associated with younger age, white race, lifetime history of overdose, history of injection drug use, past month enrollment in a substance use treatment program, past month treatment with medications for opioid use disorder, and preferences for heroin and crystal methamphetamine (all p < 0.05). Descriptive data yielded further insight into reasons for fentanyl preference, the predominant having to do with perceived effects of the drug and desire to avoid withdrawal symptoms. Only a relatively small subset of study participants preferred drugs containing fentanyl. Given the increased prevalence of fentanyl contamination across substances within the unregulated drug market, the result for PWUD is increasingly less agency with respect to choice of drug; for example, people may be forced to use fentanyl due to restricted supply and the need to mitigate withdrawal symptoms, or may be using fentanyl without intending to do so. Novel and more effective interventions for PWUD, including increased access to age-appropriate harm reduction programs such as fentanyl test strips and overdose prevention centers, are needed to mitigate fentanyl-related harms.
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来源期刊
Harm Reduction Journal
Harm Reduction Journal Medicine-Public Health, Environmental and Occupational Health
CiteScore
5.90
自引率
9.10%
发文量
126
审稿时长
26 weeks
期刊介绍: Harm Reduction Journal is an Open Access, peer-reviewed, online journal whose focus is on the prevalent patterns of psychoactive drug use, the public policies meant to control them, and the search for effective methods of reducing the adverse medical, public health, and social consequences associated with both drugs and drug policies. We define "harm reduction" as "policies and programs which aim to reduce the health, social, and economic costs of legal and illegal psychoactive drug use without necessarily reducing drug consumption". We are especially interested in studies of the evolving patterns of drug use around the world, their implications for the spread of HIV/AIDS and other blood-borne pathogens.
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