为具有依赖效应大小的荟萃分析进行功率分析:通用指南和 POMADE R 软件包简介

IF 5 2区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY Research Synthesis Methods Pub Date : 2024-09-18 DOI:10.1002/jrsm.1752
Mikkel Helding Vembye, James Eric Pustejovsky, Therese Deocampo Pigott
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引用次数: 0

摘要

在规划研究综述时,样本量和统计功率是需要考虑的重要因素。已有针对固定效应或随机效应模型的幂分析方法,但直到最近,这些方法仍局限于每项研究只有一个独立效应的简单数据结构。最近的工作为涉及具有多个依赖效应大小估计值的研究的荟萃分析提供了功率近似公式,这在社会科学研究的综合分析中很常见。之前的工作侧重于近似值的开发和验证,但并没有解决在应用这些近似值规划涉及依存效应大小的综述时遇到的实践挑战。我们的目的是通过提供实用指南,指导如何在规划依存效应大小的荟萃分析时进行功率分析,并介绍为此目的设计的新 R 软件包 POMADE,从而促进这些最新进展的应用。我们全面概述了进行功率分析所需的研究设计特征和模型参数的相关资源信息,以及使用 POMADE 软件包的详细工作示例。在展示功率分析结果时,我们强调图形工具可以描述一系列可信假设下的功率,并介绍了一种新颖的图谱--交通灯功率图,用于表达假设的确定程度。
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Conducting power analysis for meta-analysis with dependent effect sizes: Common guidelines and an introduction to the POMADE R package

Sample size and statistical power are important factors to consider when planning a research synthesis. Power analysis methods have been developed for fixed effect or random effects models, but until recently these methods were limited to simple data structures with a single, independent effect per study. Recent work has provided power approximation formulas for meta-analyses involving studies with multiple, dependent effect size estimates, which are common in syntheses of social science research. Prior work focused on developing and validating the approximations but did not address the practice challenges encountered in applying them for purposes of planning a synthesis involving dependent effect sizes. We aim to facilitate the application of these recent developments by providing practical guidance on how to conduct power analysis for planning a meta-analysis of dependent effect sizes and by introducing a new R package, POMADE, designed for this purpose. We present a comprehensive overview of resources for finding information about the study design features and model parameters needed to conduct power analysis, along with detailed worked examples using the POMADE package. For presenting power analysis findings, we emphasize graphical tools that can depict power under a range of plausible assumptions and introduce a novel plot, the traffic light power plot, for conveying the degree of certainty in one's assumptions.

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来源期刊
Research Synthesis Methods
Research Synthesis Methods MATHEMATICAL & COMPUTATIONAL BIOLOGYMULTID-MULTIDISCIPLINARY SCIENCES
CiteScore
16.90
自引率
3.10%
发文量
75
期刊介绍: Research Synthesis Methods is a reputable, peer-reviewed journal that focuses on the development and dissemination of methods for conducting systematic research synthesis. Our aim is to advance the knowledge and application of research synthesis methods across various disciplines. Our journal provides a platform for the exchange of ideas and knowledge related to designing, conducting, analyzing, interpreting, reporting, and applying research synthesis. While research synthesis is commonly practiced in the health and social sciences, our journal also welcomes contributions from other fields to enrich the methodologies employed in research synthesis across scientific disciplines. By bridging different disciplines, we aim to foster collaboration and cross-fertilization of ideas, ultimately enhancing the quality and effectiveness of research synthesis methods. Whether you are a researcher, practitioner, or stakeholder involved in research synthesis, our journal strives to offer valuable insights and practical guidance for your work.
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