减肥干预对糖尿病患者和非糖尿病患者的不同疗效

IF 3.8 3区 医学 Q2 Medicine Diabetes Therapy Pub Date : 2024-09-14 DOI:10.1007/s13300-024-01646-y
Federico Losada-Díaz, Santiago Lizarazo-Bocanegra, Juan J. Perdomo-Lugo, Sebastián A. Gutiérrez-Romero, Isabella Correa-Osio, Carlos O. Mendivil
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引用次数: 0

摘要

肥胖既是糖尿病的主要风险因素,也是糖尿病的严重并发症。在过去几十年里,肥胖症和糖尿病这两种流行病已在全球蔓延。治疗糖尿病患者的肥胖症可带来一系列临床益处,几乎涵盖身体的所有系统。尽管如此,多种证据表明,大多数减肥疗法对糖尿病患者的疗效明显降低。在此背景下,我们总结了生活方式、药物和手术治疗肥胖症对现有糖尿病患者产生不同效果的证据,并探讨了造成这种现象的潜在机制。然后利用这些信息制定策略,以改善糖尿病患者的减肥效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Differential Efficacy of Weight Loss Interventions in Patients with Versus Without Diabetes

Obesity is both a major risk factor for diabetes and a serious comorbidity of the condition. The twin epidemics of obesity and diabetes have spread globally over the past few decades. Treatment of obesity in patients with diabetes provides a host of clinical benefits that encompass virtually all body systems. Despite this, multiple lines of evidence suggest that the efficacy of most therapies for weight loss is significantly reduced among patients with diabetes. With this background, we summarize the evidence of a differential effect of lifestyle, pharmacological, and surgical treatments for obesity in patients with existing diabetes, and explore the potential mechanisms involved in this phenomenon. This information is then used to formulate strategies to improve weight loss outcomes for patients with diabetes.

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来源期刊
Diabetes Therapy
Diabetes Therapy Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
6.90
自引率
7.90%
发文量
130
审稿时长
6 weeks
期刊介绍: Diabetes Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all areas of diabetes. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Diabetes Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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