Study on ultrasound diagnosis and pathological anatomy of fetal complex congenital heart disease in the first trimester

PurposeTo assess the feasibility of using the stereo‐microscope to identify the pathological anatomy of the congenital heart diseases in the first trimester.MethodsFifteen fetuses of 8–12 weeks aborted due to prevent miscarriage failure and 42 fetuses of 11–14 weeks with congenital heart diseases were included in the study, we dissected their hearts through a stereo‐microscope, then compared with the prenatal ultrasonographic diagnosis.ResultsUsing stereomicroscopy, the positive view of the heart and the great arteries, the long axis view of the aortic arch, the inflow tract view of the bottom heart, the semilunar valve view of the bottom heart, and the transverse section of the ventricle were showed contented and obtained satisfactory images, but the structure of atrioventricular valve and venous system had a lower rate of display.ConclusionThe characteristic pathological changes of cardiac inflow and outflow tract can be obtained by dissecting the heart sequential under the stereo‐microscopy. However it is often difficult to obtain satisfactory pathological sections for pulmonary venous abnormalities and Ebstein anomaly.