非透析慢性肾病患者肥胖管理的营养评估和医学饮食疗法:内分泌医师、营养师和肾病医师实用指南。意大利内分泌学会(SIE)、营养-激素和新陈代谢俱乐部工作组、意大利营养保健品学会(SINut)、酮饮食和营养保健品俱乐部 "KetoNut-SINut "以及意大利肾脏病学会(SIN)的共识声明

IF 3.9 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM Journal of Endocrinological Investigation Pub Date : 2024-09-18 DOI:10.1007/s40618-024-02446-8
G. Annunziata, M. Caprio, L. Verde, A. M. Carella, E. Camajani, A. Benvenuto, B. Paolini, L. De Nicola, F. Aucella, V. Bellizzi, S. Barberi, D. Grassi, F. Fogacci, A. Colao, A. F. G. Cicero, F. Prodam, G. Aimaretti, G. Muscogiuri, L. Barrea
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引用次数: 0

摘要

目的 慢性肾脏病(CKD)是一个严重的健康问题,估计全球发病率约为 13.4%。慢性肾脏病是包括心血管疾病在内的多种并发症的诱因和后果。与此同时,与衰老和不健康的饮食习惯密切相关的常见病理情况也增加了慢性肾脏病发展和恶化的风险,其中包括 2 型糖尿病和肥胖症。其中,肥胖要么是新发肾病的独立风险因素,要么通过多种机制加速肾功能的衰退速度。因此,旨在减轻肥胖症患者体重的饮食显然对预防慢性肾脏病和减缓疾病进展至关重要。目前已经有多种饮食方法被许可用于慢性肾脏病的医学饮食治疗,包括低蛋白饮食和地中海饮食。有趣的是,新出现的证据也支持在这些患者中使用低碳水化合物/生酮饮食(LCD/KD)。更具体地说,低碳水化合物/生酮饮食可有效促进体重减轻、改善代谢指标、减少炎症和氧化应激,从而形成一种饮食策略,全面控制与肾功能直接或间接相关的并发症。结论本共识声明由意大利内分泌学会(SIE)、营养-激素和新陈代谢俱乐部工作组、意大利营养保健品学会(SINut)、Ketodiets 和营养保健品俱乐部 "KetoNut-SINut"、意大利肾脏病学会(SIE)、意大利内分泌学会(SIE)、意大利营养-激素和新陈代谢俱乐部工作组、意大利营养保健品学会(SINut)、Ketodiets 和营养保健品俱乐部 "KetoNut-SINut "和意大利肾脏病学会共同发表;该指南旨在为内分泌科医生、营养学家和肾脏病学家提供指导,帮助他们管理患有非透析性慢性肾脏病的肥胖患者,为评估营养状况和开具最佳饮食处方提供实用指导,从而以最佳方式管理肥胖,预防慢性肾脏病及其发展为透析。图表摘要
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Nutritional assessment and medical dietary therapy for management of obesity in patients with non-dialysis chronic kidney disease: a practical guide for endocrinologist, nutritionists and nephrologists. A consensus statement from the Italian society of endocrinology (SIE), working group of the club nutrition–hormones and metabolism; the Italian society of nutraceuticals (SINut), club ketodiets and nutraceuticals “KetoNut-SINut”; and the Italian society of nephrology (SIN)

Purpose

Chronic kidney disease (CKD) is a serious health concern with an estimated prevalence of about 13.4% worldwide. It is cause and consequence of various comorbidities, including cardiovascular diseases. In parallel, common pathological conditions closely related to ageing and unhealthy dietary habits increase the risk of CKD development and progression, including type 2 diabetes and obesity. Among these, obesity is either independent risk factor for new onset kidney disease or accelerates the rate of decline of kidney function by multiple mechanisms. Therefore, the role of diets aimed at attaining weight loss in patients with obesity is clearly essential to prevent CKD as to slow disease progression. Various dietary approaches have been licensed for the medical dietary therapy in CKD, including low-protein diet and Mediterranean diet. Interestingly, emerging evidence also support the use of low-carbohydrate/ketogenic diet (LCD/KD) in these patients. More specifically, LCD/KDs may efficiently promote weight loss, improve metabolic parameters, and reduce inflammation and oxidative stress, resulting in a dietary strategy that act globally in managing collateral conditions that are directly and indirectly related to the kidney function.

Conclusion

This consensus statement from the Italian Society of Endocrinology (SIE), working group of the Club Nutrition – Hormones and Metabolism; the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals “KetoNut-SINut”; and the Italian Society of Nephrology (SIN) is intended to be a guide for Endocrinologist, Nutritionists and Nephrologist who deal with the management of patients with obesity with non-dialysis CKD providing a practical guidance on assessing nutritional status and prescribing the optimal diet in order to best manage obesity to prevent CKD and its progression to dialysis.

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来源期刊
Journal of Endocrinological Investigation
Journal of Endocrinological Investigation 医学-内分泌学与代谢
CiteScore
8.70
自引率
7.40%
发文量
242
审稿时长
3 months
期刊介绍: The Journal of Endocrinological Investigation is a well-established, e-only endocrine journal founded 36 years ago in 1978. It is the official journal of the Italian Society of Endocrinology (SIE), established in 1964. Other Italian societies in the endocrinology and metabolism field are affiliated to the journal: Italian Society of Andrology and Sexual Medicine, Italian Society of Obesity, Italian Society of Pediatric Endocrinology and Diabetology, Clinical Endocrinologists’ Association, Thyroid Association, Endocrine Surgical Units Association, Italian Society of Pharmacology.
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