急性和慢性 PPT1 抑制对黑色素瘤的不同影响

IF 14.6 1区 生物学 Q1 CELL BIOLOGY Autophagy Pub Date : 2024-09-12 DOI:10.1080/15548627.2024.2403152
Mary Ann S. Crissey, Amanda Versace, Monika Bhardwaj, Vaibhav Jain, Shujing Liu, Arpana Singh, Lynn A. Beer, Hsin-Yao Tang, Jessie Villanueva, Phyllis A. Gimotty, Xiaowei Xu, Ravi K. Amaravadi
{"title":"急性和慢性 PPT1 抑制对黑色素瘤的不同影响","authors":"Mary Ann S. Crissey, Amanda Versace, Monika Bhardwaj, Vaibhav Jain, Shujing Liu, Arpana Singh, Lynn A. Beer, Hsin-Yao Tang, Jessie Villanueva, Phyllis A. Gimotty, Xiaowei Xu, Ravi K. Amaravadi","doi":"10.1080/15548627.2024.2403152","DOIUrl":null,"url":null,"abstract":"Macroautophagy/autophagy-lysosome function promotes growth and survival of cancer cells, making them attractive targets for cancer therapy. One intriguing lysosomal target is PPT1 (palmitoyl-protei...","PeriodicalId":8722,"journal":{"name":"Autophagy","volume":null,"pages":null},"PeriodicalIF":14.6000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Divergent effects of acute and chronic PPT1 inhibition in melanoma\",\"authors\":\"Mary Ann S. Crissey, Amanda Versace, Monika Bhardwaj, Vaibhav Jain, Shujing Liu, Arpana Singh, Lynn A. Beer, Hsin-Yao Tang, Jessie Villanueva, Phyllis A. Gimotty, Xiaowei Xu, Ravi K. Amaravadi\",\"doi\":\"10.1080/15548627.2024.2403152\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Macroautophagy/autophagy-lysosome function promotes growth and survival of cancer cells, making them attractive targets for cancer therapy. One intriguing lysosomal target is PPT1 (palmitoyl-protei...\",\"PeriodicalId\":8722,\"journal\":{\"name\":\"Autophagy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":14.6000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Autophagy\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1080/15548627.2024.2403152\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Autophagy","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/15548627.2024.2403152","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

大自噬/自噬-溶酶体功能可促进癌细胞的生长和存活,因此成为癌症治疗的诱人靶点。一个令人感兴趣的溶酶体靶点是PPT1(棕榈酰蛋白酶)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Divergent effects of acute and chronic PPT1 inhibition in melanoma
Macroautophagy/autophagy-lysosome function promotes growth and survival of cancer cells, making them attractive targets for cancer therapy. One intriguing lysosomal target is PPT1 (palmitoyl-protei...
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Autophagy
Autophagy 生物-细胞生物学
CiteScore
21.30
自引率
2.30%
发文量
277
审稿时长
1 months
期刊介绍: Autophagy is a peer-reviewed journal that publishes research on autophagic processes, including the lysosome/vacuole dependent degradation of intracellular material. It aims to be the premier journal in the field and covers various connections between autophagy and human health and disease, such as cancer, neurodegeneration, aging, diabetes, myopathies, and heart disease. Autophagy is interested in all experimental systems, from yeast to human. Suggestions for specialized topics are welcome. The journal accepts the following types of articles: Original research, Reviews, Technical papers, Brief Reports, Addenda, Letters to the Editor, Commentaries and Views, and Articles on science and art. Autophagy is abstracted/indexed in Adis International Ltd (Reactions Weekly), EBSCOhost (Biological Abstracts), Elsevier BV (EMBASE and Scopus), PubMed, Biological Abstracts, Science Citation Index Expanded, Web of Science, and MEDLINE.
期刊最新文献
Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis. Burkholderia pseudomallei BipD initiates mitophagy to evade killing by hijacking host KLHL9-KLHL13-CUL3 E3 ligase to ubiquitinate IMMT The interplay between probiotics and host autophagy: mechanisms of action and emerging insights. Divergent effects of acute and chronic PPT1 inhibition in melanoma The autophagy-repressive tissue hormone DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein) suppresses anorexia
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1