{"title":"体位感应诱发电位与经颅多普勒超声在颈动脉内膜切除术中脑缺血检测中的对比分析:来自网络 Meta 分析和临床数据的启示。","authors":"Dejing Cheng,Siyuan Yang,Chengyuan Ji","doi":"10.1016/j.wneu.2024.09.023","DOIUrl":null,"url":null,"abstract":"OBJECTIVE\r\nThis study aims to compare the diagnostic efficacy of somatosensory-evoked potentials (SEP) and transcranial Doppler sonography (TCD) for monitoring cerebral tissue ischemia during carotid endarterectomy (CEA) using network meta-analysis and retrospective analysis of clinical data.\r\n\r\nMETHODS\r\nFor the meta-analysis, we conducted a comprehensive search of four electronic databases (PubMed, EMBASE, Cochrane, and Web of Science) from inception to September 2023, resulting in the inclusion of 52 relevant articles. Additionally, a retrospective study was conducted at our hospital, involving patients who underwent CEA surgery from July 2019 to July 2021.\r\n\r\nRESULTS\r\nThe network meta-analysis incorporated 52 articles, with ranking results indicating that SEP demonstrated superior performance in specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy , with surface under the cumulative ranking curve (SUCRA) values of 99.9%, 93.8%, 96.6%, and 99.9%, respectively. Furthermore, TCD exhibited the highest sensitivity with a SUCRA value of 92.0%. A total of 190 patients meeting inclusion criteria were included in the retrospective study. The area under the curve (AUC) for SEP's receiver operating characteristic (ROC) curve was 0.787, compared to TCD's AUC of 0.606. SEP demonstrated a sensitivity of 66.67%, with a specificity of 90.76%, PPV of 19.05%, NPV of 98.82%, and accuracy of 90%. For TCD, the diagnostic performance measures included a sensitivity of 50.00%, specificity of 71.19%, PPV of 5.35%, NPV of 97.76%, and accuracy of 70.53%. The Fisher's exact test for sensitivity yielded a result of P=1.000. The χˆ2 test for specificity resulted in χˆ2=22.863, with P<0.001. Continuous correction χˆ2 tests for PPV and NPV showed χˆ2=2.005 (P=0.157) and χˆ2=0.069 (P=0.793), respectively. Additionally, the χˆ2 test for accuracy showed χˆ2=22.742, with P<0.001.\r\n\r\nCONCLUSIONS\r\nDuring CEA, SEP appears to provide a slightly more reliable indication of the ischemic condition in cerebral tissues compared to TCD.","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative Analysis of Somatosensory-evoked Potentials and Transcranial Doppler Ultrasound for Cerebral Ischemia Detection in Carotid Endarterectomy: Insights from Network Meta-Analysis and Clinical Data.\",\"authors\":\"Dejing Cheng,Siyuan Yang,Chengyuan Ji\",\"doi\":\"10.1016/j.wneu.2024.09.023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"OBJECTIVE\\r\\nThis study aims to compare the diagnostic efficacy of somatosensory-evoked potentials (SEP) and transcranial Doppler sonography (TCD) for monitoring cerebral tissue ischemia during carotid endarterectomy (CEA) using network meta-analysis and retrospective analysis of clinical data.\\r\\n\\r\\nMETHODS\\r\\nFor the meta-analysis, we conducted a comprehensive search of four electronic databases (PubMed, EMBASE, Cochrane, and Web of Science) from inception to September 2023, resulting in the inclusion of 52 relevant articles. Additionally, a retrospective study was conducted at our hospital, involving patients who underwent CEA surgery from July 2019 to July 2021.\\r\\n\\r\\nRESULTS\\r\\nThe network meta-analysis incorporated 52 articles, with ranking results indicating that SEP demonstrated superior performance in specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy , with surface under the cumulative ranking curve (SUCRA) values of 99.9%, 93.8%, 96.6%, and 99.9%, respectively. Furthermore, TCD exhibited the highest sensitivity with a SUCRA value of 92.0%. A total of 190 patients meeting inclusion criteria were included in the retrospective study. The area under the curve (AUC) for SEP's receiver operating characteristic (ROC) curve was 0.787, compared to TCD's AUC of 0.606. SEP demonstrated a sensitivity of 66.67%, with a specificity of 90.76%, PPV of 19.05%, NPV of 98.82%, and accuracy of 90%. For TCD, the diagnostic performance measures included a sensitivity of 50.00%, specificity of 71.19%, PPV of 5.35%, NPV of 97.76%, and accuracy of 70.53%. The Fisher's exact test for sensitivity yielded a result of P=1.000. The χˆ2 test for specificity resulted in χˆ2=22.863, with P<0.001. Continuous correction χˆ2 tests for PPV and NPV showed χˆ2=2.005 (P=0.157) and χˆ2=0.069 (P=0.793), respectively. Additionally, the χˆ2 test for accuracy showed χˆ2=22.742, with P<0.001.\\r\\n\\r\\nCONCLUSIONS\\r\\nDuring CEA, SEP appears to provide a slightly more reliable indication of the ischemic condition in cerebral tissues compared to TCD.\",\"PeriodicalId\":23906,\"journal\":{\"name\":\"World neurosurgery\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World neurosurgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.wneu.2024.09.023\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World neurosurgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.wneu.2024.09.023","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Comparative Analysis of Somatosensory-evoked Potentials and Transcranial Doppler Ultrasound for Cerebral Ischemia Detection in Carotid Endarterectomy: Insights from Network Meta-Analysis and Clinical Data.
OBJECTIVE
This study aims to compare the diagnostic efficacy of somatosensory-evoked potentials (SEP) and transcranial Doppler sonography (TCD) for monitoring cerebral tissue ischemia during carotid endarterectomy (CEA) using network meta-analysis and retrospective analysis of clinical data.
METHODS
For the meta-analysis, we conducted a comprehensive search of four electronic databases (PubMed, EMBASE, Cochrane, and Web of Science) from inception to September 2023, resulting in the inclusion of 52 relevant articles. Additionally, a retrospective study was conducted at our hospital, involving patients who underwent CEA surgery from July 2019 to July 2021.
RESULTS
The network meta-analysis incorporated 52 articles, with ranking results indicating that SEP demonstrated superior performance in specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy , with surface under the cumulative ranking curve (SUCRA) values of 99.9%, 93.8%, 96.6%, and 99.9%, respectively. Furthermore, TCD exhibited the highest sensitivity with a SUCRA value of 92.0%. A total of 190 patients meeting inclusion criteria were included in the retrospective study. The area under the curve (AUC) for SEP's receiver operating characteristic (ROC) curve was 0.787, compared to TCD's AUC of 0.606. SEP demonstrated a sensitivity of 66.67%, with a specificity of 90.76%, PPV of 19.05%, NPV of 98.82%, and accuracy of 90%. For TCD, the diagnostic performance measures included a sensitivity of 50.00%, specificity of 71.19%, PPV of 5.35%, NPV of 97.76%, and accuracy of 70.53%. The Fisher's exact test for sensitivity yielded a result of P=1.000. The χˆ2 test for specificity resulted in χˆ2=22.863, with P<0.001. Continuous correction χˆ2 tests for PPV and NPV showed χˆ2=2.005 (P=0.157) and χˆ2=0.069 (P=0.793), respectively. Additionally, the χˆ2 test for accuracy showed χˆ2=22.742, with P<0.001.
CONCLUSIONS
During CEA, SEP appears to provide a slightly more reliable indication of the ischemic condition in cerebral tissues compared to TCD.
期刊介绍:
World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The journal''s mission is to:
-To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care.
-To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide.
-To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients.
Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS