Flavia T. T. Antunes, Maria A. Gandini, Vinicius M. Gadotti, Nara Lins Meira Quintão, José Roberto Santin, Ivana A. Souza, Laurence S. David, Terrance P. Snutch, Michael Hildebrand, Gerald W. Zamponi
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引用次数: 0
摘要
化疗药物奥沙利铂可引起奥沙利铂诱导的周围神经病变(OIPN)。在此,我们研究了 T 型钙通道(Cav3)是否对 OIPN 起作用。
Contribution of T-type calcium channel isoforms to cold and mechanical sensitivity in naïve and oxaliplatin-treated mice of both sexes
The chemotherapy agent oxaliplatin can give rise to oxaliplatin-induced peripheral neuropathy (OIPN). Here, we investigated whether T-type calcium channels (Cav3) contribute to OIPN.
期刊介绍:
The British Journal of Pharmacology (BJP) is a biomedical science journal offering comprehensive international coverage of experimental and translational pharmacology. It publishes original research, authoritative reviews, mini reviews, systematic reviews, meta-analyses, databases, letters to the Editor, and commentaries.
Review articles, databases, systematic reviews, and meta-analyses are typically commissioned, but unsolicited contributions are also considered, either as standalone papers or part of themed issues.
In addition to basic science research, BJP features translational pharmacology research, including proof-of-concept and early mechanistic studies in humans. While it generally does not publish first-in-man phase I studies or phase IIb, III, or IV studies, exceptions may be made under certain circumstances, particularly if results are combined with preclinical studies.