急诊科医生成功实施主动脉血管内球囊闭塞复苏术(REBOA),治疗难治性非外伤性心脏骤停

IF 2.1 Q3 CRITICAL CARE MEDICINE Resuscitation plus Pub Date : 2024-09-21 DOI:10.1016/j.resplu.2024.100784
Graham Brant-Zawadzki , Guillaume L. Hoareau , H. Hill Stoecklein , Nicholas Levin , Craig H. Selzman , Anna Ciullo , Joseph Tonna , Christopher Kelly , Jamal Jones , Scott T. Youngquist , M. Austin Johnson
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引用次数: 0

摘要

目标美国每年有 60 多万人因心脏骤停而死亡。几十年来,心脏骤停患者的存活率一直停滞不前。主动脉血管内球囊闭塞复苏术(REBOA)最常用于治疗严重失血性休克,主要用于治疗不可压缩的胸腹部创伤。越来越多的证据表明,它可以在非创伤性、难治性心脏骤停中起到增强心脑灌注的作用。REBOA 通常由介入放射科医生在实时透视下实施。我们描述了一项由急诊科医生主导的培训计划和治疗方案,该计划和方案是为了在急诊科为院外难治性心脏骤停且不符合 ECPR 条件的患者实施 REBOA。我们详细介绍了培训、认证过程以及前八个病例的临床结果。结果五名急诊科医生通过授课课程以及人体模型和活体组织猪模型的实践培训,接受了安置 REBOA 的培训。自协议实施以来,急诊科医生已为 8 名患者进行了 REBOA 导管置入术:其中男性 5 人,女性 3 人,年龄在 25-79 岁之间。首次成功率为 8/8(100%),成功使用了美国所有 3 种市售导管。3/8(37.5%)名患者获得了 ROSC,但没有患者存活到出院。结论该系列研究表明,急诊医生为非创伤性难治性心脏骤停患者置入 REBOA 是一种新型复苏技术。通过集中教育、创新技术应用、基于大型动物模型的有力培训和战略性程序整合,我们展示了急诊科率先采用这种可能挽救生命的干预措施的潜力。
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Successful Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) deployment by emergency medicine physicians for refractory non-traumatic cardiac arrest

Aim

Cardiac arrest afflicts over 600,000 people annually in the United States. Rates of survival from cardiac arrest have remained stagnant for decades. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is most commonly used in the management of severe hemorrhagic shock, primarily for non-compressible thoracoabdominal trauma. A growing body of evidence suggests it may serve a role in augmenting cardiac and cerebral perfusion in non-traumatic, refractory cardiac arrest. Typically, REBOA is deployed by interventional radiologists under real-time fluoroscopy. Limited data exist to demonstrate the feasibility or logistics of successful REBOA deployment in emergency departments by emergency medicine physicians.

Methods

We describe an emergency medicine-driven training program and treatment protocol developed to deploy REBOA in the emergency department for patients experiencing refractory out-of-hospital cardiac arrest and deemed ineligible for ECPR. We detail the training, certification processes, and clinical outcomes from our first eight cases.

Results

Five emergency medicine physicians underwent training for REBOA placement through a didactic curriculum and hands-on training with mannequin and live tissue porcine models. Since protocol implementation, eight patients have undergone REBOA catheterization by emergency medicine physicians: 5 males and 3 females, age range 25–79. The first pass success was 8/8 (100 %), and all 3 commercially available catheters in the United States were successfully used. ROSC was achieved in 3/8 (37.5 %) patients, although no patients survived to hospital discharge. No REBOA catheter-associated complications were identified.

Conclusions

This series demonstrates feasibility of emergency physician placed REBOA for non-traumatic, refractory cardiac arrest a novel resuscitative technique. Through a combination of focused education, innovative technology use, robust large animal model-based training, and strategic procedural integration, we showcase the potential for emergency departments to spearhead the adoption of this potentially life-saving intervention.

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来源期刊
Resuscitation plus
Resuscitation plus Critical Care and Intensive Care Medicine, Emergency Medicine
CiteScore
3.00
自引率
0.00%
发文量
0
审稿时长
52 days
期刊最新文献
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