Fe(III)-catalyzed p-selective C-H bond chalcogenation of phenols.

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2024-09-11 Epub Date: 2024-09-09 DOI:10.1039/d4ob01382d
Biprajit Paul , Sayak Ghosh , Surajit Das , Indranil Chatterjee
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引用次数: 0

摘要

本研究介绍了一种高效、环保和可扩展的苯酚对选择性 C-X(X = Se/S)键形成方案,该方案采用了富集的、毒性较低的铁(III)催化剂和绿色溶剂乙醇,无需使用任何导向模板、稳定配体、氧化剂或添加剂。该方法的主要吸引力在于:在温和的有氧反应条件下,具有令人印象深刻的对选择性和适度至良好的产率、广泛的官能团兼容性,以及可对产品进行合成改性,使其成为具有附加值的分子。
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Fe(iii)-catalyzed p-selective C–H bond chalcogenation of phenols†
An efficient, eco-friendly, and scalable protocol has been introduced for the p-selective C–X (X = Se/S) bond formation of phenols employing earth-abundant, less-toxic Fe(iii)-catalysts and the green solvent ethanol without using any directing template, stabilizing ligands, oxidants, or additives. The key attraction lies in the impressive p-selectivity with moderate to good yields, wide functional group compatibility under mild aerobic reaction conditions, and the synthetic modification of the products towards value-added molecules.
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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
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