吡唑多组分合成的最新进展。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-09-10 DOI:10.1039/D4OB01211A
Jing Zhou, Quanquan Zhou and Jie-Ping Wan
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引用次数: 0

摘要

吡唑分子被认为是药物和许多其他功能分子中重要的 N-杂环。利用多组分反应是目前吡唑合成方法中的一个主要工具。考虑到多组分吡唑合成的能力和意义,我们在此综述了该领域的最新进展。根据典型特征,内容分为肼、腙、脒、腈和重氮化合物等不同 NN 片段源在吡唑环构建中的反应,涵盖了自 2019 年至今发表的作品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recent advances in the multicomponent synthesis of pyrazoles

Pyrazole moiety is considered as an important N-heterocycle in pharmaceuticals and many other functional molecules. The utilization of multicomponent reaction is a major tool in the current approaches of pyrazole synthesis. Considering the power and significance of multicomponent pyrazole synthesis, we review herein the latest developments in this field. According to the typical features, the contents are divided into reactions with different NN fragment sources, such as hydrazine, hydrazone, amidine, nitrile, and diazo compounds, in the pyrazole ring construction, covering the works published since 2019 to date.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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