葡萄糖和钠水平作为危重病人疾病预后的预测指标。

IF 0.7 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Acta clinica Croatica Pub Date : 2023-11-01 DOI:10.20471/acc.2023.62.03.13
Željka Dragila, Andrea Dorokazi, Damir Mihić, Domagoj Loinjak, Miroslav Šram, Tatjana Bačun
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引用次数: 0

摘要

本研究的主要目的是探讨葡萄糖和钠水平与危重症患者的诊断和疾病预后之间的关联。研究回顾了 2015 年 11 月 1 日至 2017 年 2 月 28 日期间内科重症监护室收治的 283 名危重患者的葡萄糖和钠浓度。危重病人最常见的诊断是急性肾损伤(26.1%)和败血症(包括脓毒性休克,22.3%)。急性肾损伤患者的葡萄糖浓度明显较低(P=0.02),而败血症和脓毒性休克患者的钠浓度明显较高(P=0.04)。葡萄糖水平越高,死亡率越高(p=0.001)。另一方面,钠浓度与存活率无明显关系。65 岁以上的患者死亡率较高,葡萄糖浓度也较高(p=0.05)。
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GLUCOSE AND SODIUM LEVELS AS DISEASE OUTCOME PREDICTORS IN CRITICALLY ILL PATIENTS.

The main aim of this study was to examine the association of glucose and sodium level with diagnosis and disease outcome of critically ill patients. Glucose and sodium concentrations of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of Internal Medicine in a period from November 1, 2015 to February 28, 2017 were reviewed. The most common diagnoses in critically ill patients were acute kidney injury (26.1%) and sepsis (including septic shock, 22.3%). Significantly lower glucose concentration was observed in patients with acute kidney injury (p=0.02), whereas patients in sepsis and septic shock had a significantly higher sodium concentration (p=0.04). Higher glucose level was related to higher mortality rate (p=0.001). On the other hand, sodium level was not significantly associated with survival. Higher mortality, as well as higher glucose concentration were more common in patients older than 65 years (p<0.001). Study results showed significantly lower glucose concentrations in patients with acute kidney injury, whereas in patients older than 65, glucose concentration was significantly higher. Patients in sepsis and septic shock had significantly higher sodium concentrations. Higher concentration of glucose was connected with higher mortality in the elderly, whereas sodium concentration did not show connection with mortality.

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来源期刊
Acta clinica Croatica
Acta clinica Croatica 医学-医学:内科
CiteScore
1.10
自引率
16.70%
发文量
38
审稿时长
6-12 weeks
期刊介绍: Acta Clinica Croatica is a peer reviewed general medical journal that publishes original articles that advance and improve medical science and practice and that serve the purpose of transfer of original and valuable information to journal readers. Acta Clinica Croatica is published in English four times a year.
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