一名人类免疫缺陷病毒 (HIV) 阳性患者的肝脏肿块。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY ACG Case Reports Journal Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI:10.14309/crj.0000000000001481

Reanay Berezovskiy, James M Crawford, Arvind Rishi, Sohil Khurana, Joshua Kern, Stefani Morscher, Sanjaya K Satapathy

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引用次数: 0

摘要

IgG4 相关疾病（IgG4-RD）是一种自身免疫综合征，其特点是血清 IgG4 水平升高，IgG4 免疫反应性浆细胞浸润各种组织类型。IgG4-RD 可导致全身性疾病，并形成炎性肿块病变，常被称为假瘤。虽然 IgG4-RD 可表现为各种器官的病变，但肝脏受累却很少见，而且由于它是一种免疫介导的炎症过程，因此在免疫力低下的患者中并不常见。此外，尽管 IgG4-RD 对免疫抑制治疗反应良好，但自发缓解的病例在文献中极为罕见。在本报告中，我们介绍了一例艾滋病毒阳性患者肝脏 IgG4-RD 病变自我缓解的独特病例。

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An Evasive Liver Mass in a Human Immunodeficiency Virus (HIV)-Positive Patient.

IgG4-related disease (IgG4-RD) is an autoimmune syndrome that is characterized by elevated levels of serum IgG4 and infiltration of various tissue types by IgG4 immunoreactive plasma cells. The IgG4-RD can result in systemic disease and the formation of inflammatory mass lesions, frequently addressed as pseudotumors. While IgG4-RD can manifest in various organs, liver involvement is rare, and because it is an immune-mediated inflammatory process, it is uncommon in patients who are immunocompromised. Furthermore, despite IgG4-RD responding well to immunosuppressive treatment, cases of spontaneous remission are exceedingly rare in the literature. In this report, we present the unique case of a self-resolving IgG4-RD lesion of the liver in a HIV positive patient.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.