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引用次数: 0
摘要
背景：A 群链球菌可引起多种人类感染，其中包括危及生命的坏死性筋膜炎，患者可能对此视而不见。从数个小时到数天不等，感染可能会从表面上看似良性的皮肤损伤（通常被误认为是蜘蛛或昆虫叮咬）发展为高度致命的疾病。我们报告了一例 57 岁男性左上肢皮肤肿胀的病例：表皮分泌物和血液中的 A 组链球菌（GAS）、β 型溶血性链球菌均呈阳性。患者接受了强化抗感染治疗。然而，肢体坏死情况迅速恶化。13 天后，他死于多器官衰竭、链球菌中毒性休克综合征（STSS）和弥散性血管内凝血：结论：坏死性筋膜炎是一种进展迅速的破坏性细菌感染。结论：坏死性筋膜炎是一种进展迅速的破坏性细菌感染，早期识别是患者存活的最重要因素。
Necrotizing Fasciitis Caused by Group A Streptococcus.
Background: Group A Streptococcus causes a variety of human infections, including the life-threatening necrotizing fasciitis, which may be ignored by the patient. From hours to days, the infection may progress from an apparently benign skin lesion, usually mistaken for a spider or insect bite, to a highly lethal disease. We present a case of 57-year-old male with skin lesions on swelling left upper limb.
Methods and results: The culture of secretion from epidermis and blood were positive for Group A Streptococcus (GAS), type β hemolytic streptococcus. Intensive anti-infection therapy was applied. However, the necrosis of the limb deteriorated rapidly. He died from multiple organ failure, streptococcal toxic shock syndrome (STSS) and disseminated intravascular coagulation 13 days later.
Conclusions: Necrotizing fasciitis is a rapidly progressive, destructive bacterial infection. Early recognition is the most important factor for survival.
期刊介绍：
Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
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