电子人工尿道括约肌:经典设备的不断创新--叙述式回顾。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-31 Epub Date: 2023-06-30 DOI:10.21037/tau-22-858
George E Koch, Melissa R Kaufman
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引用次数: 0

摘要

背景和目的:现代人工尿道括约肌(AUS)得益于渐进式创新,提高了设备功效和并发症发生率,而波士顿科技公司的 AMS800 所采用的基础技术可追溯到 AS721 的基本液压原理。自适应技术和电子集成方面的研究与开发将进一步改善 AUS 的疗效:使用不同组合的 MeSH 术语 "人工尿道括约肌"、"电子"、"并发症"、"历史 "和 "发展 "查询 Medline 在线检索系统。如果适用,则对出版物进行审查,并根据需要使用参考文献列表收集其他文章。主要内容和研究结果:AMS800 AUS是男性压力性尿失禁植入物的黄金标准。2015 年的一次共识会议提出了未来几十年括约肌装置的发展目标。未来理想的括约肌将动态调节充气罩囊压力,并以最少的操作甚至通过电子控制实现功能。多种新设备正处于不同的开发阶段。在未来十年中,人工尿道括约肌技术可能会包括多种获得美国食品药品管理局(FDA)批准的设备,这些设备具有不同的功能,旨在满足 2015 年共识会议提出的 "理想 "人工尿道括约肌的目标:压力性尿失禁治疗的未来取决于 AUS 的持续创新以及再生医学的进步。AUS 技术的电子化和适应性发展将提高设备的安全性、有效性和使用寿命,同时改善使用者和护理人员的体验。对某些人来说,再生医学甚至可能使 AUS 技术过时。
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The electronic artificial urinary sphincter: ongoing innovation of a classic device-a narrative review.

Background and objective: While the modern artificial urinary sphincter (AUS) has benefited from incremental innovation, which has improved both device efficacy and complication rates, the foundational technology in use in Boston Scientific's AMS800 can be traced back to the fundamental hydraulic tenets of the AS721. Research and development in adaptive technology and electronic integration stand to further improve AUS outcomes.

Methods: The Medline online retrieval system was queried using the MeSH terms "artificial urinary sphincter", "electronic", "complications", "history", and "development" in various combinations. Publications were reviewed if applicable, and their reference lists were used to collect additional articles as needed. Final article inclusion was based on senior author discretion.

Key content and findings: The AMS800 AUS is the gold standard for male stress incontinence implants. A 2015 consensus conference set out the goals for sphincter device development in the coming decades. A future ideal sphincter would adjust cuff pressure dynamically as well as function with minimal manipulation, or even via electronic control. Multiple new devices are in various states of development. During the next decade, artificial urinary sphincter technology is likely to include multiple Food and Drug Administration (FDA)-approved devices with varying features aimed at satisfying the 2015 consensus conference goal for an "ideal" AUS.

Conclusions: The future of stress incontinence therapy lies in both continued innovation for the AUS, as well as advances in regenerative medicine. Electronic and adaptive developments in AUS technology will increase device safety, efficacy, and longevity while improving the user and caregiver experience. For some, regenerative medicine may even make AUS technology obsolete.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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