利用基于深度学习的超分辨率重建技术提高腹部计算机断层扫描的空间分辨率并减少辐射剂量:模型研究。

IF 4.7 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Academic Radiology Pub Date : 2025-03-01 Epub Date: 2024-09-20 DOI:10.1016/j.acra.2024.09.012
Yoshinori Funama , Yasunori Nagayama , Daisuke Sakabe , Yuya Ito , Yutaka Chiba , Takeshi Nakaura , Seitaro Oda , Masafumi Kidoh , Toshinori Hirai
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引用次数: 0

摘要

理论依据和目标:本研究评估了基于深度学习的超分辨率重建(SR-DLR)的性能,并将其与混合迭代重建(HIR)和正常分辨率 DLR(NR-DLR)进行了比较,以提高不同视场(FOV)大小、辐射剂量和降噪强度的计算机断层扫描(CT)图像的质量:使用一个装有体外环的 Catphan 模型。使用滤波背投影(FBP)、HIR、NR-DLR 和 SR-DLR,在三种降噪强度(轻微、标准和强烈)下重建 CT 图像。从不同视场角、辐射剂量和降噪强度下的 FBP、HIR、NR-DLR 和 SR-DLR 图像中获得噪声功率谱(NPS)。使用 NPS 计算了 HIR、NR-DLR 和 SR-DLR 图像相对于 FBP 图像的噪声幅度比 (NMR) 和中心频率比 (CFR)。高对比度值从轮廓曲线的峰值和谷值的振幅值中获得,基于任务的传递函数也得到了分析:SR-DLR 始终表现出卓越的降噪能力,减量时的 NMR 为 0.29-0.36,标准剂量时为 0.35-0.45,优于 HIR,与 NR-DLR 的效率相当。在低剂量和标准剂量下,SR-DLR 的高对比度值在轻度和标准剂量下都是最高的(轻度剂量下分别为 0.610 和 0.726,标准剂量下分别为 0.725 和 0.603)。在标准剂量下,SR-DLR 的空间分辨率显著提高,与降噪强度和 FOV 无关:SR-DLR图像的降噪效果比HIR更显著,降噪效果与NR-DLR重建相似,同时还提高了空间分辨率。
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Advances in spatial resolution and radiation dose reduction using super-resolution deep learning–based reconstruction for abdominal computed tomography: A phantom study

Rationale and Objectives

This study evaluated the performance of super-resolution deep learning-based reconstruction (SR-DLR) and compared with it that of hybrid iterative reconstruction (HIR) and normal-resolution DLR (NR-DLR) for enhancing image quality in computed tomography (CT) images across various field of view (FOV) sizes, radiation doses, and noise reduction strengths.

Materials and Methods

A Catphan phantom equipped with an external body ring was used. CT images were reconstructed using filtered back-projection (FBP), HIR, NR-DLR, and SR-DLR across three noise reduction strengths: mild, standard, and strong. The noise power spectrum (NPS) was obtained from the FBP, HIR, NR-DLR, and SR-DLR images at various FOVs, radiation doses, and noise reduction strengths. The noise magnitude ratio (NMR) and central frequency ratio (CFR) were calculated from the HIR, NR-DLR, and SR-DLR images relative to the FBP images using NPS. The high-contrast value was obtained from the amplitude values of the peaks and valleys of profile curve and the task-based transfer function were also analyzed.

Results

SR-DLR consistently demonstrated superior noise reduction capabilities, with NMR of 0.29–0.36 at reduced dose and 0.35–0.45 at standard dose, outperforming HIR and showing comparable efficiency to NR-DLR. The high-contrast values for SR-DLR were highest at mild and standard levels for both low and standard doses (0.610 and 0.726 at mild and 0.725 and 0.603 at standard levels). At the standard dose, the spatial resolution of SR-DLR was significantly improved, regardless of the noise reduction strength and FOV.

Conclusion

SR-DLR images achieved more substantial noise reduction than HIR and similar noise reduction as NR-DLR reconstructions while also improving spatial resolution.
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来源期刊
Academic Radiology
Academic Radiology 医学-核医学
CiteScore
7.60
自引率
10.40%
发文量
432
审稿时长
18 days
期刊介绍: Academic Radiology publishes original reports of clinical and laboratory investigations in diagnostic imaging, the diagnostic use of radioactive isotopes, computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound, digital subtraction angiography, image-guided interventions and related techniques. It also includes brief technical reports describing original observations, techniques, and instrumental developments; state-of-the-art reports on clinical issues, new technology and other topics of current medical importance; meta-analyses; scientific studies and opinions on radiologic education; and letters to the Editor.
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