股网膜疾病的治疗范围和血管内治疗后的临床效果。

IF 7.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Eurointervention Pub Date : 2024-09-16 DOI:10.4244/EIJ-D-24-00037
Yong-Hoon Yoon, Jae-Hwan Lee, Won-Mook Hwang, Hyun-Woong Park, Jae-Hyung Roh, Seung-Jun Lee, Young-Guk Ko, Chul-Min Ahn, Cheol Woong Yu, Seung-Whan Lee, Young Jin Youn, Jong Kwan Park, Chang-Hwan Yoon, Seung-Woon Rha, Pil-Ki Min, Seung-Hyuk Choi, In-Ho Chae, Donghoon Choi, Of The K-Vis Investigators On Behalf
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引用次数: 0

摘要

背景:血管内治疗(EVT)已成为股骨干疾病的首选治疗方式。目的:本研究旨在根据股浅动脉(SFA)、腘动脉(PA)或两者的治疗范围调查临床结果和设备效果:在这项研究中,我们利用 K-VIS ELLA(韩国血管介入协会下肢动脉疾病血管内治疗)登记人口,分析了针对 SFA(2404 个肢体)、PA(155 个肢体)、SFA/PA(383 个肢体)的 EVT。主要终点是2年后的靶病变血管再通(TLR):结果:SFA/PA组解剖结构复杂,病变长、中度至重度钙化和全闭塞的发生率较高。97.2%的SFA、92.9%的PA和95.6%的SFA/PA EVT手术成功。SFA组、PA组和SFA/PA组的2年TLR率分别为21.1%、18.6%和32.7%。与SFA组相比,SFA/PA EVT与TLR风险显著增加有关(调整后危险比[HR] 1.48 [1.09-2.00]; p=0.008),与PA组相比,TLR风险呈增加趋势(调整后HR 1.80 [1.00-3.27]; p=0.052)。经过重叠加权后,使用药物涂层球囊(DCB)被证明是有益的,SFA和SFA/PA EVT后的TLR率最低:结论:在这一大型真实世界登记中,与SFA或PA EVT组相比,SFA/PA EVT与2年后TLR风险增加有关,SFA/PA EVT组使用DCB或药物洗脱支架的结果较好。
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Treatment extent of femoropopliteal disease and clinical outcomes following endovascular therapy.

Background: Endovascular therapy (EVT) has become the preferred treatment modality for femoropopliteal disease. However, there is limited evidence regarding its procedural and clinical outcomes according to the affected area.

Aims: The aim of this study is to investigate clinical outcomes and device effectiveness according to treatment extent in the superficial femoral artery (SFA), popliteal artery (PA), or both.

Methods: In this study, we analysed EVT for SFA (2,404 limbs), PA (155 limbs), SFA/PA (383 limbs) using the population in the K-VIS ELLA (Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases) registry. The primary endpoint was target lesion revascularisation (TLR) at 2 years.

Results: The SFA/PA group exhibited a higher prevalence of anatomical complexity, characterised by long lesions, moderate to severe calcification, and total occlusion. The procedures were successful in 97.2% of SFA, 92.9% of PA, and 95.6% of SFA/PA EVTs. The 2-year TLR rates were 21.1%, 18.6%, and 32.7% in the SFA, PA, and SFA/PA groups, respectively. SFA/PA EVT was associated with a significantly increased risk for TLR compared to the SFA group (adjusted hazard ratio [HR] 1.48 [1.09-2.00]; p=0.008) and a trend towards an increased risk compared to the PA group (adjusted HR 1.80 [1.00-3.27]; p=0.052). After overlap weighting, the use of a drug-coated balloon (DCB) was shown to be beneficial, with the lowest TLR rate after SFA and SFA/PA EVT.

Conclusions: In this large real-world registry, SFA/PA EVT was associated with an increased risk for TLR at 2 years compared to the SFA or PA EVT groups, with favourable outcomes when using a DCB or drug-eluting stent in the SFA/PA EVT group.

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来源期刊
Eurointervention
Eurointervention CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
10.30
自引率
4.80%
发文量
380
审稿时长
3-8 weeks
期刊介绍: EuroIntervention Journal is an international, English language, peer-reviewed journal whose aim is to create a community of high quality research and education in the field of percutaneous and surgical cardiovascular interventions.
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