Yong-Hoon Yoon, Jae-Hwan Lee, Won-Mook Hwang, Hyun-Woong Park, Jae-Hyung Roh, Seung-Jun Lee, Young-Guk Ko, Chul-Min Ahn, Cheol Woong Yu, Seung-Whan Lee, Young Jin Youn, Jong Kwan Park, Chang-Hwan Yoon, Seung-Woon Rha, Pil-Ki Min, Seung-Hyuk Choi, In-Ho Chae, Donghoon Choi, Of The K-Vis Investigators On Behalf
{"title":"股网膜疾病的治疗范围和血管内治疗后的临床效果。","authors":"Yong-Hoon Yoon, Jae-Hwan Lee, Won-Mook Hwang, Hyun-Woong Park, Jae-Hyung Roh, Seung-Jun Lee, Young-Guk Ko, Chul-Min Ahn, Cheol Woong Yu, Seung-Whan Lee, Young Jin Youn, Jong Kwan Park, Chang-Hwan Yoon, Seung-Woon Rha, Pil-Ki Min, Seung-Hyuk Choi, In-Ho Chae, Donghoon Choi, Of The K-Vis Investigators On Behalf","doi":"10.4244/EIJ-D-24-00037","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Endovascular therapy (EVT) has become the preferred treatment modality for femoropopliteal disease. However, there is limited evidence regarding its procedural and clinical outcomes according to the affected area.</p><p><strong>Aims: </strong>The aim of this study is to investigate clinical outcomes and device effectiveness according to treatment extent in the superficial femoral artery (SFA), popliteal artery (PA), or both.</p><p><strong>Methods: </strong>In this study, we analysed EVT for SFA (2,404 limbs), PA (155 limbs), SFA/PA (383 limbs) using the population in the K-VIS ELLA (Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases) registry. The primary endpoint was target lesion revascularisation (TLR) at 2 years.</p><p><strong>Results: </strong>The SFA/PA group exhibited a higher prevalence of anatomical complexity, characterised by long lesions, moderate to severe calcification, and total occlusion. The procedures were successful in 97.2% of SFA, 92.9% of PA, and 95.6% of SFA/PA EVTs. The 2-year TLR rates were 21.1%, 18.6%, and 32.7% in the SFA, PA, and SFA/PA groups, respectively. SFA/PA EVT was associated with a significantly increased risk for TLR compared to the SFA group (adjusted hazard ratio [HR] 1.48 [1.09-2.00]; p=0.008) and a trend towards an increased risk compared to the PA group (adjusted HR 1.80 [1.00-3.27]; p=0.052). After overlap weighting, the use of a drug-coated balloon (DCB) was shown to be beneficial, with the lowest TLR rate after SFA and SFA/PA EVT.</p><p><strong>Conclusions: </strong>In this large real-world registry, SFA/PA EVT was associated with an increased risk for TLR at 2 years compared to the SFA or PA EVT groups, with favourable outcomes when using a DCB or drug-eluting stent in the SFA/PA EVT group.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 18","pages":"e1154-e1162"},"PeriodicalIF":7.6000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384224/pdf/","citationCount":"0","resultStr":"{\"title\":\"Treatment extent of femoropopliteal disease and clinical outcomes following endovascular therapy.\",\"authors\":\"Yong-Hoon Yoon, Jae-Hwan Lee, Won-Mook Hwang, Hyun-Woong Park, Jae-Hyung Roh, Seung-Jun Lee, Young-Guk Ko, Chul-Min Ahn, Cheol Woong Yu, Seung-Whan Lee, Young Jin Youn, Jong Kwan Park, Chang-Hwan Yoon, Seung-Woon Rha, Pil-Ki Min, Seung-Hyuk Choi, In-Ho Chae, Donghoon Choi, Of The K-Vis Investigators On Behalf\",\"doi\":\"10.4244/EIJ-D-24-00037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Endovascular therapy (EVT) has become the preferred treatment modality for femoropopliteal disease. However, there is limited evidence regarding its procedural and clinical outcomes according to the affected area.</p><p><strong>Aims: </strong>The aim of this study is to investigate clinical outcomes and device effectiveness according to treatment extent in the superficial femoral artery (SFA), popliteal artery (PA), or both.</p><p><strong>Methods: </strong>In this study, we analysed EVT for SFA (2,404 limbs), PA (155 limbs), SFA/PA (383 limbs) using the population in the K-VIS ELLA (Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases) registry. The primary endpoint was target lesion revascularisation (TLR) at 2 years.</p><p><strong>Results: </strong>The SFA/PA group exhibited a higher prevalence of anatomical complexity, characterised by long lesions, moderate to severe calcification, and total occlusion. The procedures were successful in 97.2% of SFA, 92.9% of PA, and 95.6% of SFA/PA EVTs. The 2-year TLR rates were 21.1%, 18.6%, and 32.7% in the SFA, PA, and SFA/PA groups, respectively. SFA/PA EVT was associated with a significantly increased risk for TLR compared to the SFA group (adjusted hazard ratio [HR] 1.48 [1.09-2.00]; p=0.008) and a trend towards an increased risk compared to the PA group (adjusted HR 1.80 [1.00-3.27]; p=0.052). 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Treatment extent of femoropopliteal disease and clinical outcomes following endovascular therapy.
Background: Endovascular therapy (EVT) has become the preferred treatment modality for femoropopliteal disease. However, there is limited evidence regarding its procedural and clinical outcomes according to the affected area.
Aims: The aim of this study is to investigate clinical outcomes and device effectiveness according to treatment extent in the superficial femoral artery (SFA), popliteal artery (PA), or both.
Methods: In this study, we analysed EVT for SFA (2,404 limbs), PA (155 limbs), SFA/PA (383 limbs) using the population in the K-VIS ELLA (Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases) registry. The primary endpoint was target lesion revascularisation (TLR) at 2 years.
Results: The SFA/PA group exhibited a higher prevalence of anatomical complexity, characterised by long lesions, moderate to severe calcification, and total occlusion. The procedures were successful in 97.2% of SFA, 92.9% of PA, and 95.6% of SFA/PA EVTs. The 2-year TLR rates were 21.1%, 18.6%, and 32.7% in the SFA, PA, and SFA/PA groups, respectively. SFA/PA EVT was associated with a significantly increased risk for TLR compared to the SFA group (adjusted hazard ratio [HR] 1.48 [1.09-2.00]; p=0.008) and a trend towards an increased risk compared to the PA group (adjusted HR 1.80 [1.00-3.27]; p=0.052). After overlap weighting, the use of a drug-coated balloon (DCB) was shown to be beneficial, with the lowest TLR rate after SFA and SFA/PA EVT.
Conclusions: In this large real-world registry, SFA/PA EVT was associated with an increased risk for TLR at 2 years compared to the SFA or PA EVT groups, with favourable outcomes when using a DCB or drug-eluting stent in the SFA/PA EVT group.
期刊介绍:
EuroIntervention Journal is an international, English language, peer-reviewed journal whose aim is to create a community of high quality research and education in the field of percutaneous and surgical cardiovascular interventions.