坦桑尼亚达累斯萨拉姆特梅克 6 至 59 个月儿童贫血的严重程度和形态特征:基于诊所的横断面分析

The East African health research journal Pub Date : 2024-01-01 Epub Date: 2024-06-26 DOI:10.24248/eahrj.v8i2.780
Salha Ally Omary, Florence Salvatory Kalabamu, Maulidi Rashidi Fataki, Shani Shamsi Salum, Ummulkheir Hamid Mohamed, Joseph Gasper Kimaro, Kelvin Melkizedeck Leshabari
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引用次数: 0

摘要

背景:贫血是一个全球性的公共健康指标,既表明营养不良,也表明健康状况不佳。此外,贫血还是人类整个生命周期中卫生系统失调的无声信号。在全球范围内,贫血在儿童中的重要性最为突出。本研究旨在评估坦桑尼亚达累斯萨拉姆特梅克 6 至 59 个月大儿童贫血的严重程度和形态特征:我们设计了一项以诊所为基础的横断面分析研究。目标人群为 6 至 59 个月大的贫血儿童。贫血的严重程度和形态特征是主要的结果变量。数据通过预先设计的问卷收集。数据汇总采用中位数和四分位数间距(连续变量)或频率和比例(分类变量)。采用卡方检验来评估分类变量之间的关联。研究结果的第一类误差以 5%为限。在纳入研究之前,我们征得了每位儿童母亲的书面知情同意:我们成功招募并分析了 250 名儿童。参与者的年龄中位数为 17.5 个月(IQR:9 - 34)(女性,112 人,44.8%)。贫血点患病率(HbP=.000)。所研究儿童的贫血患病率和严重程度之间存在明显关联(LR χ2 (corrected) = 229.5, df=3)。大多数儿童(121 人,72%)患有正常血细胞正常色素性贫血:结论:在 Temeke 门诊就诊的大多数五岁以下儿童都患有贫血症。正常血色素正常红细胞性贫血是该研究人群中最常见的贫血类型。
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Severity and Morphological Characteristics of Anaemia Among 6 to 59 Months Old Children in Temeke, Dar es Salaam-Tanzania: Clinics Based Cross Sectional Analysis.

Background: Anaemia is a global public health indicator of both poor nutrition and poor health. Besides, it stands as a silent signal of mal-aligned health system across the entire human lifespan. Globally, the importance of anaemia is most pronounced among children. This study was conceived to assess severity and morphological characteristics of anaemia among children aged from 6 to 59 months old in Temeke, Dar es Salaam, Tanzania.

Methods: We designed a cross sectional, clinics-based analytical study. Children aged 6 to 59 months with anaemia were the target population. Severity and morphological characteristics of anaemia were the main outcome variables. Data were collected using a pre-designed questionnaire. Data were summarised using median and inter-quartile range (continuous variables) or frequency and proportions (categorical variables). Chi-square tests were applied to assess association between categorical variables. Alpha level of 5% was used as a limit of type 1 error in findings. Written informed consent was sought from mother of each child prior to inclusion into the study.

Results: We successfully recruited and analysed 250 children. Participants median age was 17.5 (IQR: 9 - 34) months (females, n=112, 44.8%). Point prevalence of anaemia (Hb<12 g/dL) was 66.8%. Among anemic children (n=167), about 19%, 63% and 18% had mild, moderate and severe anaemia respectively. A direct linear association between MCV and MCHC was observed among anemic children (n=167, Spearman's rank ´Y= 0.86, P=.000). There was a significant association between prevalence and severity of anaemia among studied children (LR χ2 (corrected) = 229.5, df=3). Majority (n=121, 72%) of the studied children had normocytic normochromic anaemia.

Conclusion: Majority of under-fives in attendance at outpatient clinics in Temeke were anemic. Normochromic normocytic anaemia was the most prevalent variant of anaemia in this study population.

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