慢性阻塞性肺病需要新的分类系统。

Esra Ertan Yazar
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引用次数: 0

摘要

目前的分类无法完全满足医生和慢性阻塞性肺病患者在临床实践中的需求。未来的分类应旨在预防高危人群的疾病发展,在不可逆转的损害发生之前实现早期诊断,识别亚组,并提供病理生理学见解以启发药物开发。作为新分类的潜在补充,全面检查和评估各种致病因素是合理的,如(FEV1)年下降率增加、支气管高反应性、可变阻塞、FEV1 预测百分比、血嗜酸性粒细胞计数、肺活量保留比值受损(PRISm)和 B 组亚群。
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The need for a new classification system in chronic obstructive pulmonary disease.

The current classification fails to fully meet the needs of physicians and COPD patients in clinical practice. The future classification should aim to prevent the development of disease in high-risk groups, enable early diagnosis before irreversible damage occurs, identify subgroups, and provide pathophysiological insight to inspire drug development. It would be reasonable to thoroughly examine and assess the contributing factors such as an increase in the annual decline of (FEV1), bronchial hyperresponsiveness, variable obstruction, FEV1 % predicted, blood eosinophil count, preserved ratio impaired spirometry (PRISm), and the subgroups of group B as potential additions to the new classification.

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