了解和预防肥胖相关结肠癌的进展。

IF 2.6 4区医学 Q3 ONCOLOGY Cancer journal Pub Date : 2024-09-01 DOI:10.1097/PPO.0000000000000744

Christine Shieh, Henry J Thompson, Eric McLaughlin, Chien-Wei Chiang, Hisham Hussan

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引用次数: 0

摘要

摘要：肥胖症和结肠直肠癌是全球性的公共卫生问题，这两种疾病的发病率在过去 40 年中不断上升。仅在美国，肥胖症的发病率就超过了 40%，预计到 2030 年，这一比例将超过 50%。本综述侧重于了解肥胖与结肠直肠癌风险之间的联系，同时还强调了有关这些疾病过程之间联系的分子机制的假设。我们还考虑了是否可以通过减肥疗法（包括改变生活方式、药物疗法、减肥手术和减肥内科手术）来破坏这些联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advancements in Understanding and Preventing Obesity-Related Colon Cancer.

Abstract: Obesity and colorectal cancer are global public health issues, with the prevalence of both conditions increasing over the last 4 decades. In the United States alone, the prevalence of obesity is greater than 40%, and this percentage is projected to increase past 50% by 2030. This review focuses on understanding the association between obesity and the risk of colorectal cancer while also highlighting hypotheses about molecular mechanisms underlying the link between these disease processes. We also consider whether those linkages can be disrupted via weight loss therapies, including lifestyle modifications, pharmacotherapy, bariatric surgery, and endobariatrics.

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来源期刊

Cancer journal 医学-肿瘤学

CiteScore

3.90

自引率

0.00%

发文量

102

审稿时长

7.5 months

期刊介绍： The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.